Sentence examples for major degradative response from inspiring English sources

It would therefore appear that the full cellulolytic arsenal is expressed as part of the late-onset major degradative response.

These genes are considered to be part of the early and major degradative response of A. niger respectively.

During the later (24 h), major degradative response to wheat straw, a greater number of CAZy enzyme-encoding genes showed increased transcription levels when compared to 6 h exposure to wheat straw, these encoded mainly cellulolytic and pectinolytic enzymes.

Here, we investigate the full scope of the early and major degradative response of A. niger to wheat straw, as well as the early and late carbon starvation response using RNA-Seq.

Comparison of the late, major degradative response to straw to prolonged (24 h) carbon starvation, showed that genes encoding enzymes that are involved in autolytic degradation of the fungal cell wall, exhibit increased transcript levels under both conditions.

We previously showed in a time course experiment of A. niger exposed to ball-milled wheat straw, that some genes were up-regulated between 3 and 6 h after transfer to wheat straw (named the early degradative response), while genes of the major degradative response were up-regulated later, between 6 and 9 h after transfer (Delmas et al., 2012).

Relief of carbon catabolite repression, by glucose depletion or deletion of creA, was found to activate expression of genes of this early degradative response, while expression levels of genes of the major, later, degradative response were not affected (Delmas et al., 2012).

These genes are part of the early degradative response, and encode enzymes that could have a 'scouting' role during lignocellulose degradation.

Relaxing the strict regulation of cysteine is crucial for its overproduction; therefore, identifying and modulating the major degradative activity could facilitate the genetic engineering of a cysteine-producing strain.

Our study also indicates that the proteasomal pathway is unlikely to be a major degradative pathway for ErbB2 under steady state conditions as we do not see any accumulation of ErbB2 upon POH1 knockdown as measured by FACS analysis.

To determine the region of BRCA1 that confers the degradative response to γ irradiation, we generated a series of BRCA1 deletion mutants and examined the stability of these BRCA1 mutants using an in vitro protein degradation assay (Figure 4A and B) [34].