Sentence examples for major pathological response from inspiring English sources

Only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib.

We presented the first case of ALK-rearranged lung adenocarcinoma with major pathological response in resected specimens after treatment with alectinib.

Pathological examination revealed that only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib (Fig. 3).

Here, we present the first surgical case of ALK-rearranged lung adenocarcinoma with major pathological response in resected specimens after treatment with alectinib.

Bevacizumab in combination with oxaliplatin/fluoropyrimidines can provide the highest major pathological response rate [15], and the pathological response to induction chemotherapy has been shown to correlate with improved survival [16].

Here, we report the first case of ALK-rearranged lung adenocarcinoma with major pathological response in resected specimens after treatment with alectinib, which may provide a pathological rationale for its greater clinical efficacy for advanced patients and may warrant clinical trials of adjuvant treatment of alectinib for resectable ALK-rearranged NSCLC patients.

Seven of 10 patients with PDA had major pathological responses.

Of the 10 patients with PDA, 1 had a complete pathological response, 6 had major pathological responses (GRT-1), 1 had a partial response (GRT-2) and 2 did not response (GRT-3).

Major and minor pathological responses were seen in eight patients.

Thus, in a total of 32 patients (61.5%) a major or complete pathological response to preoperative chemoradiation was found.

The 100% complete resection rate and high number of patients with a major or complete pathological response might explain the lack of survival benefit in patients who had a pCR.