Ai Feedback
Exact(5)
Thirty-eight patients had a first major amputation during the follow-up period.
Among the patients in our study, 15.4% had a first major amputation during follow-up.
Being on renal replacement therapy at the time of inclusion (HR, 3.51 [95% CI, 1.02 12.07]; P = 0.046) was an independent predictive variable for a first major amputation during follow-up in our study.
Secondary endpoint was death or development of PAD defined as any of: loss of foot pulse, development of ankle-brachial index <0.9, lower limb revascularization or major amputation during follow up.
There was no statistical difference in the risk of a first major amputation during the follow-up period between patients who had undergone a minor amputation before inclusion in the study when this factor was included as an additional covariate (HR, 1.21 [95% CI, 0.56 2.59]; P = 0.630) in model 1 of Table 3.
Similar(55)
A total of 231 patients were submitted to major amputations during this period and 17 (7.3%) were rehospitalized due to amputation stump infections of which 5 (29.4%) died within one month.
During the two year follow-up 22 subjects underwent major amputation (major amputation rate during follow-up 3.2%).
32 subjects with diabetic foot in the structured health care group underwent major amputation (amputation above the ankle) during hospital treatment (major amputation rate 4.7%).
The purpose of our study is therefore to report risk factors associated with first major amputation as well as mortality during a long-term observation period of at least 10 years in a cohort of consecutively presenting patients with diabetic foot ulcers.
In a study investigating a large cohort of diabetic foot patients (n = 1,088) treated at centers of excellence in 10 different European countries, the major amputation rate among patients with PAD during a 12-month follow-up was 8%, compared with 2% among patients without PAD (P < 0.001 1313).
A first major amputation occurred in 38 patients (15.4%) during follow-up.
Related(20)
major currency during
major issue during
major tool during
major thrust during
major problem during
major disruption during
major decision during
major trauma during
major role during
major process during
major target during
major hit during
major incident during
major crash during
major bleeding during
major disagreement during
major damage during
major moneymaker during
major tournament during
major speech during
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com