Sentence examples for maintains its expression from inspiring English sources

Therefore, it is helpful to have a marker at hand, which maintains its expression qualitatively even in poorly differentiated carcinomas.

The above results strongly indicate that HPV E7 in some way targets the cellular SIRT1 protein and maintains its expression at abnormally high levels in cervical cancer cells.

For example in the Drosophila embryo, the Hox factor Ubx maintains its expression or even completely represses its expression in different tissues through negative autoregulation (Irvine et al. 1993).

MLL binds to specific clusters of CpG islands of HOXA9, adjacent to miR-196b, and maintains its expression by protecting these clusters from DNA methylation (Erfurth et al, 2008).

In contrast, the α6 integrin maintains its expression in adenomas, but its expression levels are very low in malignancies with infiltrative growth characteristics, suggesting an association with CRC progression [ 12].

This shows that signaling between CdxA expressing cells is normally needed to maintain its expression.

Regulating mechanisms that maintain its expression could turn to be a potential tumor regulator due to tumor suppressor functions.

We first examined the expression of Foxp3 since we had found that NOD APC were defective at maintaining its expression in CD4+CD25+ cells in vitro (Table 2).

We also note that TLRs stated to form at fatal stage and maintained its expression level after birth, which agrees with previous reports [29] [30].

In this way Nodal signalling is both upstream of the AVE, as it induces AVE gene expression [20], and downstream of this tissue, as some AVE genes, such as Bmp2, are required to maintain its expression.

Furthermore, our choice to express the fusion protein from an inducible promoter on a plasmid rather than from a modified chromosomic copy was made in order to strictly control the amount of the protein present in the cell, to maintain its expression level close to the physiological one or to overexpress Hfq-MT when it is necessary in order to characterize the biological system.