Sentence examples for maintained in undifferentiated from inspiring English sources

To our knowledge, this study is the first report showing that mouse ES (mES) cells can be maintained in undifferentiated state on hydroxyapatite coated with gelatin.

While it is possible to prospectively isolate progenitors [12]_ENREF_11 and to demonstrate their differentiation potential they cannot be reliably maintained in undifferentiated state in culture.

Moreover, these floating neurospheres can be maintained in undifferentiated proliferative state for at least 14-DIV (including 1 passage after 7-DIV) by culture in medium with growth factors (Figure 1-C).

TF-1 cells are committed early erythroid CD34+ cells, which are maintained in undifferentiated state in the presence of IL-3 or GM-CSF [ 24].

(A – D ) Lateral views, anterior to the left, of embryos at 18 hpf show that differentiating myoblasts adjacent to the notochord lose tsp4b mRNA while expression is maintained in undifferentiated mesoderm cells, located laterally.

PPARG has been reported to repress prostate cancer under some undetermined mechanisms [ 28], mainly due to the disadvantage made by adipogenesis for a cell to maintain in undifferentiated state.

Mouse trophoblast stem cells (B6TS4 line) derived from a C57BL/6 N blastocyst in our laboratory were cultured and maintained in an undifferentiated state in the 70CM + F4H medium51.

These findings indicate that mES cells can be cultured under serum- and feeder-free conditions and maintained in an undifferentiated state on a composite with hydroxyapatite and that this composite can be used to control the differentiation of stem cells.

It was found that while both compositions allowed for the colonisation of mouse ES cells, the cells were not maintained in an undifferentiated state, as evidenced by a reduction in the number of cells staining positive for Oct4 expression.

It thus seems that let-7 should be expressed at specific stages of terminal differentiation, but down-regulated in stem cells being maintained in their undifferentiated state.

Indeed, most H9 hES cells cultured with bFGF-expressing hFLSCs were maintained in an undifferentiated state.