Sentence examples for maintained by telomerase from inspiring English sources

For example, trypanosomatid telomeres are maintained by telomerase and consist of the canonical TTAGGG repeats, which in Trypanosoma brucei can form telomeric loops (t-loops).

Telomeres are specialized structures at the end of eukaryotic chromosomes that function to prevent chromosome end-joining and maintained by telomerase, a ribonucleoprotein complex that functions in elongating telomeres using reverse transcriptase and a specific RNA molecule in the complex.

In these cases, telomeres are still maintained by telomerase, if homologous recombination is impossible due to a deletion of RAD52 (Zubko and Lydall 2006).

Like most organisms whose telomeres are maintained by telomerase, the ends of S. cerevisiae chromosomes consist of nonprotein coding repeated DNA.

However, in the case of tpz1-K75A cells, the short telomeres are maintained by telomerase because they were lost completely after further deletion of the trt1+ gene.

Telomere length is maintained by the ALT pathway in U2OS cells, whereas in other cell lines telomere length can be maintained by telomerase (Cesare and Reddel, 2010).

In highly proliferating cells, such as the germ and stem cells, telomere length is maintained by the telomerase enzyme, whereas in somatic cells, the activity of telomerase is low, leading to progressive telomere shortening with age, providing a marker for cellular aging [1], [2].

Usually, telomere length is maintained by the telomerase, containing the reverse transcriptase TERT and the RNA template TERC, as well as associating proteins such as the ribonucleoprotein dyskerin (DKC1) (Cohen et al., 2007).

Thus, short telomeres in tpz1-K75A mutares are maintained by impaired telomerase activity.

Fission yeast telomeres, like those of other species, can be maintained by either telomerase action or by recombination.

In most organisms, telomeres are composed of simple repetitive sequences whose length is maintained by the telomerase ribonucleoprotein.