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In conclusion, transcriptional repression of a large number of ncRNAs by p53/CEP-1 importantant for its ability to maintain chromosome stability with underlying mechanism and unknown functional consequences of transcriptional repression.
Homologous recombination (HR) can maintain chromosome stability by using the sister chromatid or homologous chromosome as a template for repair.
XRCC2 and XRCC3 mediate RecA/Rad51-related proteins involved in homologous recombination to maintain chromosome stability and repair of double-strand breaks in DNA damage.
The Rad51‐related protein XRCC3 plays roles in the recombinational repair of DNA double‐strand breaks to maintain chromosome stability and repair DNA damage.
Genes that maintain chromosome stability are found in all cells and are highly conserved among eukaryotes, probably due to the essential nature of DNA replication, repair, and segregation.
Telomeres are nucleoprotein structures located at the ends of chromosomes that perform a capping function to maintain chromosome stability and integrity.
Similar(51)
Mammalian telomeres are specialized chromatin structures that require the telomere binding protein, TRF2, for maintaining chromosome stability.
It not only plays an important role in maintaining chromosome stability but also helps in protecting of the coding parts of the DNA for recombination, degradation and replication damage.
In the diploid hfi1Δ strain, all cells demonstrated complete conversion to the MATa mating phenotype while in the ctf4Δ mutant, high rates of conversion to both MATa or MATα was observed consistent with the described role of Ctf4 in maintaining chromosome stability and sister chromatid cohesion [94].
One of the major devices for maintaining chromosome stability during cell division is the CPC.
The appropriate expression of spindle assembly checkpoint (SAC) factors may be an important factor for maintaining chromosome stability.
Related(11)
preserve chromosome stability
maintain chromosome mobility
maintain chromosomal stability
maintain community stability
maintain chromosome integrity
maintain chromosome territoriality
maintain chromosome condensation
maintain price stability
maintain chromosome structure
maintain chromosome length
maintain chromosome homomorphy
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