Sentence examples for mainly upstream of from inspiring English sources

The amino acid length (152 amino acids) and the 7C were well conserved between the members, with polymorphism mainly upstream of the first domain and the inter-domain region.

We have also shown that neither exogenous PGE2 [17] nor iloprost (a stable PGI2 analogue; not shown) stimulate VEGFR2 Tyr1175 phosphorylation in ECs, providing further support for the suggestion that leptin/VEGFR2 interactions are mainly upstream of prostanoid synthesis.

Regulation of apoptosis occurs mainly upstream of mitochondrial changes, through the altered expression and/or posttranslational modification of pro- and anti-apoptotic Bcl-2 family members.

In addition to TNFα we studied the expression of other cytokines such as IL18, which is believed to operate mainly upstream of TNFα, while IL1β and IL6 appear to act mainly downstream of TNFα.

It has been shown that genes that are silenced in cancer are often the same genes marked by EZH2 in normal cells, an observation suggesting that EZH2 acts mainly upstream of methylation or in its initiation.

H2A.Z is enriched mainly upstream of the TSS in human [ 1], both upstream and downstream in mouse and yeast [ 30, 31], but mainly downstream of the TSS in Drosophila [ 32] and Arabidopsis [ 33].

Transcription of tDNAs is not affected due to Isw2 loss [ 13] probably because Isw2 on tDNAs maintains mainly upstream nucleosome periodicity.

Tidal elevation mainly increases upstream of the tidal array, while a decrease is observed downstream, along the UK east coast.

The combustion process mainly occurs upstream of the injection port, and it makes a great difference to the wall pressure distribution upstream of the injection port, especially when the jet-to-crossflow pressure ratio is large enough, namely 17.72 and 25.15 in the range considered in the current study.

When the cavitation number decreases, the cavity initially generates on the suction side of the blade near the leading edge and then expands to the outlet of the impeller, and the decrease of the total pressure coefficient mainly occurs upstream of the impeller passage, while the downstream remains almost unaffected by the development of cavitation.

The T-boxes reported so far in literature were mainly located upstream of tRNA-ligase encoding genes in species of the phylum Firmicutes [ 7, 26].