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RhoA lies upstream of MLC-2 and controls MLC-2 activation.
In the control of the AER, Wnt3 lies upstream of BMP ligands (Barrow et al., 2003) and Dkk1 interacts with BMPs in this context, as they can mutually induce each others expression (Mukhopadhyay et al., 2001; Grotewold and Rüther, 2002).
The region of peak association lies upstream of LOXL1-AS1, a long non-coding RNA (lncRNA) encoded on the opposite strand of LOXL1.
These results suggest that the generation of ROS by Nox4 lies upstream of GADD153.
The results shown above indicate that NF-Y lies upstream of Ash2L recruitment and H3K4me3 deposition.
c-Src lies upstream of K-ras, and we next sought to explore whether c-Src is also activated by hypoxia.
It lies upstream of a major redox-sensitive pathway leading not only to the induction of apoptosis but also to cell proliferation and differentiation [40].
A second mTOR-containing protein complex, mTORC2, lies upstream of Akt and contributes to Akt activation by insulin and growth factors by phosphorylating S473 in its hydrophobic regulatory motif [44].
A ChIP experiment with an antibody directed against the NF-κB subunit p65/RelA revealed the presence of p65/RelA in LPS-stimulated cells at region 2, which lies upstream of the second exon.
Recently we have reported a novel type of functional tRNA gene in a primitive red alga, Cyanidioschyzon merolae, in which the 3' half of the tRNA sequence lies upstream of the 5' half in the genome [19].
Here we show that the integration site of the A17-Myf5-nlacZ-T55 transgene lies upstream of Hes1, encoding a basic helix-loop-helix containing transcriptional repressor required for the maintenance of diverse progenitor cell populations during embryonic development.
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