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Two main underlying mechanisms were identified for the effects of biochar application on soil thermal properties.
In this context, myocardial ischaemia is one of the main underlying mechanisms leading to necrosis of myocardial cells defining the myocardial infarction (MI).
It has been demonstrated recently that cell cycle inhibition and induction of apoptosis are the main underlying mechanisms involved in anticancer activity of curcumin (Aggarwal et al. 2003a, b; Joe et al. 2004; Thangapazham et al. 2006).
Original viral stimuli and/or autoimmune processes are commonly considered to be the main underlying mechanisms. 2 7 14 15 Antimyolemmal and sarcolemmal antibodies were also identified in some idiopathic cases, which gave rise to the autoimmune hypothesis.
It was also shown that the main underlying mechanisms of action of curcumin were probably based on the modulation of multiple important cellular signaling pathways including NF- κB [ 5, 14].
Given that there was some residual risk for colorectal neoplasia among individuals with the GG group, it appears unlikely that the G-to-A polymorphism is one of the main components and main underlying mechanisms for some nonsyndromic cases of familial colorectal cancer.
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As of this writing, the predominant view is that instabilities in subcellular calcium handling are the main underlying mechanism.
The main underlying mechanism by which the aforementioned fluorescent proteins are phototoxic and cytotoxic is that these proteins are capable of generating and releasing several different types of ROS.
Some suggest diffusion as the main underlying mechanism involved (e.g. [6]), while others argue that early European agriculture was developed independently by indigenous Mesolithic hunter-gatherer-forager populations with no diffusion of either knowledge or people from the core SW Asian regions [4].
Current drugs and main underlying mechanism are discussed separately (Table 1).
The main underlying mechanism for this is blockade of the interaction of phosphodiesterase (PDE) type 4D with the cardiac β2AR, which is normally mediated by the actions of GRK2 and βarrs on the receptor.
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