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PAI-1, the main physiological inhibitor of plasminogen activators is involved in pathological angiogenesis at least by controlling extracellular proteolysis and by regulating endothelial cell survival and migration.
PAI-1 is a 50 kDa glycoprotein and the main physiological inhibitor of urokinase/tissue plasminogen activators (uPA/tPA), both major regulators of the fibrinolytic system.
We incubated aliquots of supernatant from degranulated pig PMNs (10 cells) with α1-Pi, the polyvalent circulating inhibitor of human NSPs, and with ACT, the main physiological inhibitor of cat G.
27 Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of both the urokinase-type plasminogen activator and the tissue plasminogen activator and thereby plays an important role in regulation of the fibrinolytic system.
Because phosphorylation inhibits ACC activity, the level of malonyl-CoA, which is a main physiological inhibitor of CPT-I (a rate-limiting enzyme of fatty acid metabolism), is reduced.
Similar(55)
It is the most abundant proteinase inhibitor within the lung whose main physiological target is neutrophil elastase (9, 35).
AT is the most abundant proteinase inhibitor within the lung whose main physiological target is neutrophil elastase.
It is a member of the serine proteinase inhibitor (serpin) family and inhibits proteases in general, including trypsin, chymotrypsin, plasma kallikrein, but its main physiological activity is very rapid inhibition of plasmin by forming a stable complex with this proteinase [ 42].
The main physiological parameters did not differ between groups.
Subsequent sections are focused into main physiological categories and the temporal advancements within these physiological windows.
The main physiological process affecting nutrient concentrations in litter is the resorption of foliar nutrients.
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