Sentence examples for main selective inhibitor from inspiring English sources

We further found that the LC3A/B-II expression was induced by sirolimus, a main selective inhibitor of mTOR, and the sirolimus-induced LC3A/B-II was partially reduced by rTF exposure, but was fully suppressed in the presence of rFVII or PAR2 agonist (see Supplementary Figure 1).

One of its main active ingredients, theophylline, is a selective inhibitor of cyclic nucleotide phosphodiesterases (PDE), which hydrolyses the second messengers, cAMP and cGMP.

PD98059 is a highly selective inhibitor of MAP kinase kinase activation, resulting in decreased phosphorylation of ERK1 and ERK2 [15], Our main conclusion is that molecular mechanisms of cortical map plasticity involve ERK1/2 activation.

Celecoxib is a cox-2 selective inhibitor.

A FAK selective inhibitor TAE-226, blocked TXA2 generation.

U0126 (selective inhibitor of MAPK/ERK), SB202190 (selective inhibitor of p38), and SP600125 (selective inhibitor of JNK) were purchased from Biomol (Plymouth Meeting).

Thus, one of the main challenges for researchers in the field is the development of potent and selective inhibitors that can mount a sustained blockade of SphK1 activity in vivo.

Using this information, we generated selective inhibitors.

Also, dual inhibitors share properties with both groups of selective inhibitors.

COX-2 selective inhibitors are associated with myocardial infarction (MI).

PLD1 and PLD2 selective inhibitors were purchased from Cayman chemical.