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While the resulting K M values were too high to allow a reliable fitting of the individual K M and vmax values, the vmax/ K M values, which represent the most valuable parameter to compare enzyme activities, were well defined.
This seems to be caused by the fact that the channeling phenomenon occurred at small b m values, which disappeared in accordance with the progress of shear process and transformed into a uniform flow.
However, in most networks this motif type is only observed a few times (low # m values) which may result in unreliable estimates.
If m1 > m2, pre-activation of Cell1 leads to its dominance together with inhibition of Cell2, in a range of m values which increases with the activation time difference.
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The program geNorm (Steiger et al. 2010) classifies genes according to the control gene stability measure (M value), which represents the average of the pair-wise variation of a gene with all other control genes.
The next occurrence of P-frame is calculated from the M value which will be FM+1S i, and it corresponds to the 6th slot of memory address with α>0.
3) Control LOESS normalization: We fit a LOESS curve only using the 199 control probes, and for each M value which corresponds to an A value, we have Mnew = M- fcontrol(A).
Measures of glucose variability from the CGMS were 1) SD of the mean of the sensor values, 2) mean amplitude of glycemic excursion (MAGE) (18, 19), and 3) M value, which is expressed by the formula below (19).
For statistical analysis, we used the log2 ratio of the intensities of methylated probe and unmethylated probe, also called M value, which is more statistically valid for the differential analysis of methylation levels [ 67].
For this reason, instead of calculating the number of immigrants (2 Nm), we discuss the M value which represents the immigration rates scaled for the mutation rate per site per generation (m/μ) and which indicates the relative contribution of migration over mutation processes to the variation observed.
Moreover, estimates of the attentional dwell time range between 200 and 400 ms, values which are incompatible with the attentional shift time estimated from the set-size slope [2], [3].
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Justyna Jupowicz-Kozak
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