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A patient-realistic torso phantom was developed with liver and lung organs and multi-positional lesions.
As the time post-injection increased, the amount of NP-CIK cells in tumor sites also increased, but there are still NP-CIK cells located in liver, spleen, kidney, and lung organs.
Liver, kidney, heart, and lung organs were dissected and collected from each rat.
But, with the increased treatment of resveratrol, the metastatic lesions in the liver and lung organs decreased.
Afterwards, both of the lung organs were excised, fixed with 10% neutral buffered formalin, and paraffin-embedded.
The lung organs were fixed with Bouin solution, paraffin-embedded and cut into 5 μm slides along the maximum area, and examined microscopically following H.E. staining.
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The current 'state of the art' for high-fidelity complex scaffolding in lung tissue engineering is the use of decellularized cadaveric lungs, which provides a unique platform for whole lung organ engineering.
In the present study, lung tissue was also affected by NiNPs even though they were administrated intraperitonealy and this shows NiNPs through circulation have reached to lung organ and caused adverse biological reactions.
We therefore explored whether FGF-10, a central inducer of airway outgrowth, induced vascular differentiation in murine fetal lung organ explants.
SCGB3A2 plays a role in lung development as demonstrated using ex vivo embryonic lung organ cultures in the presence of SCGB3A2, and in vivo by administration of SCGB3A2 to pregnant female mice, followed by examination of pre-term pups [ 4].
To further characterize the changes that occur in the pre-metastatic lungs we compared the cytokines released in pre-metastatic lung organ cultures from S100A4 MEF versus S100A4 MEF boosted tumor-bearing mice using a cytokine antibody array.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com