Sentence examples for lead to aggravation from inspiring English sources

Over time, lipotoxicity will lead to aggravation of insulin resistance, and finally to cardiac dysfunction [ 4].

It may lead to aggravation of motor symptoms due to reduced capability of taking anti PD therapy orally [ 9].

The result may indicate that increase of plasma homocysteine can lead to aggravation of the cognitive dysfunction in AD patients, which is consistent with previous reports [ 25].

In contrast to the NTG effect in stenotic CAD, where the drug had been proven to restore myocardial ischemia in coronary sinus studies [ 78], nitroglycerin can lead to aggravation of myocardial ischemia in patients with CAE and without obstructive lesions [ 48].

The inability to escape a string of high blood sugar readings – hyperglycemia – or a pattern of lows, leads to aggravation and stress.

When rules make no sense and you know it, the pilot knows it and the flight attendants know it and yet, they demand you follow those idiotic rules for the sake of nameless bureaucrats in Washington D.C., it leads to aggravation and, in the case of someone like Baldwin, an eruption.

CD4+CD25+ cells are important in controlling the pathogenesis of CIA, and depletion of CD25+ cells with anti-CD25 antibody led to aggravation of joint inflammation [ 87, 88].

PPARα insufficiency further leads to aggravation of NASH [52] which is accentuated in ATGL-KO mice due to the lack of ATGL-mediated generation of FAs as ligands for PPARα [3].

All recurrences were at the same disc space as the first extrusion, led to aggravation of paraparesis, were identified by computer tomography (CT) and were confirmed by a second surgery.

Concordantly, inhibition of circulating IL-2 led to aggravation of diverse autoimmune manifestations in NOD mice [ 45], and both IL-2-deficient and IL-2Rα-deficient C57BL/6 mice present with exocrine gland inflammation and hyposalivation [ 91, 92].

Since TH-positive cells dominate the later phase of collagen type II-induced arthritis in the joint (they are also present in synovial inflammation in chronic rheumatoid arthritis), it is not surprising that depletion of these cells by sympathectomy leads to aggravation of arthritis in the late phase [ 51].