Sentence examples for lead to aggravated from inspiring English sources

We hypothesized that the additive effects of cell-free Hb and hyperoxemia would result in a potentiated induction of harmful mechanisms related to cell-free hemoglobin toxicity and thereby lead to aggravated tissue damage.

In the individual host, co-infection may lead to aggravated disease, often resulting from extracellular cooperativity of independently replicating viruses, by which one virus modulates the host response to infection to the benefit of the other [49], [50].

All these oxidative factors might lead to aggravated tissue damage during stomach ulceration.

However, the experiments were performed with healthy animals; concurrent infections, impaired immune functions, and changing viral characteristics might lead to aggravated infections.

It has been suggested that UF-heparin may lead to aggravated hyperlipidemia during long term treatment in patients on chronic HD [ 24, 25].

Considering that exaggerated and dysregulated HMGB1 release may lead to aggravated inflammation and tissue destruction in chronic arthritis, the results of the present study suggest that HMGB1 may serve as a possible TNF-independent target molecule for biological therapy.

Pending a ruling on the precise maritime border, the tribunal told both countries to "pursue co-operation and refrain from any unilateral action that might lead to aggravating the dispute".

Never go for an inexperienced dentist as it will only lead to aggravating your problem rather than fixing it.

The significant decrease of catalyst activity and selectivity leads to aggravated thermal cracking reactions and reduced selectivities of desired products in the second half of the riser reactor.

Recently, the zebrafish has been successfully used to unravel the role of dysregulated Tnf levels during mycobacterial disease, showing that either too little or too much Tnf leads to aggravated infection (Tobin et al., 2010; Tobin et al., 2012).

Furthermore, there are a number of experimental studies showing that dexamethasone provokes an increase of apoptotic cells in the SGZ of the dentate gyrus [ 31, 66, 67], which leads to aggravated learning impairments in PM survivors [ 31].