largely mediated by

USAGE SUMMARY

The phrase "largely mediated by" is correct and usable in written English.
It can be used to describe a situation where something is primarily influenced or facilitated by another factor or entity. Example: "The success of the project was largely mediated by the collaboration between the two departments."

✓ Grammatically correct

Science

News & Media

Academia

Human-verified examples from authoritative sources

Exact Expressions

59 human-written examples

Flow-mediated dilation is largely mediated by endothelial NO production [ 26, 27].

Critical Care

This adhesion is largely mediated by a large and complex number of adhesion molecules expressed on the cell surface [ 1].

BMC Cancer

Even Bostrom's marriage is largely mediated by technology.

The New Yorker

As expected, most of these differences were largely mediated by an increased body mass index.

American Journal of Obstetrics and Gynecology

In summary, our data demonstrate that metabolic benefits of IF are largely mediated by adipose thermogenesis without overall caloric reduction.

Nature

Esophageal peristalsis consists of sequential contraction of the circular muscles of the muscularis propria, which is largely mediated by acetylcholine.

Nature

Intriguingly, however, the link between bacteria and weight-gain was largely mediated by behavior — the mice with the altered microbiome ate significantly more.

The New Yorker

Fetal growth is largely mediated by the placenta, which, like the fetus is genetically XX or XY.

Placenta

The influence of catchment topography and scale appeared to be largely mediated by their influence on soil cover and distribution.

Journal of Hydrology

(Flavour as opposed to the tastes of sweetness, saltiness, bitterness, and sourness is largely mediated by the olfactory nerve).

Encyclopedia Britannica

Human-verified similar examples from authoritative sources

Similar Expressions

1 human-written examples

This residual Nck binding is likely to be largely mediated by WIP, as it still binds N-WASPΔNck.

Current Biology

Expert writing Tips

Best practice

When using "largely mediated by", ensure that the sentence clearly identifies both the process or outcome and the primary factor influencing it. For example: "The immune response is largely mediated by T-cells."

Common error

Avoid using "largely mediated by" when the influence is only partial or uncertain. Use qualifiers such as "partially mediated by" or "potentially mediated by" when the degree of influence is not fully established.

Linguistic Context

The phrase "largely mediated by" functions as a prepositional phrase that modifies a verb or noun, indicating the means or mechanism through which an action or process primarily occurs. Ludwig examples show this phrase being used to describe how effects, benefits, or processes are mainly facilitated or influenced.

Expression frequency: Very common

Frequent in

Science

75%

Academia

13%

News & Media

12%

Less common in

Encyclopedias

0%

Formal & Business

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, the phrase "largely mediated by" is a versatile tool for expressing that a process or outcome is primarily influenced by a specific factor. As confirmed by Ludwig, its grammatical structure is correct and frequently encountered, especially in formal and scientific writing. When using this phrase, ensure that you clearly identify both the result and its primary cause to avoid ambiguity. While "largely mediated by" is generally appropriate for professional contexts, remember to consider alternative phrasing, such as "primarily influenced by" or "mainly driven by", depending on the desired emphasis. The abundance of examples from diverse fields, including science, news and media, and academia, underscores the wide-ranging applicability of this phrase.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

primarily influenced by

Emphasizes the dominant influence of one factor over another.

heavily influenced by

Emphasizes the strong influence of a particular agent or factor.

mainly driven by

Highlights the driving force or key factor behind a process or outcome.

largely controlled by

Highlights that a specific factor exerts most of the control.

mostly regulated by

Indicates that the regulation is predominantly exerted by a specific factor.

substantially governed by

Indicates a significant degree of control or regulation exerted by something.

significantly shaped by

Focuses on how something has been prominently molded or influenced.

principally caused by

Indicates the main cause or origin of something.

predominantly affected by

Focuses on the major impact or effect of a particular element.

chiefly determined by

Suggests that the primary determinant or deciding factor is something specific.

FAQs

How can I use "largely mediated by" in a sentence?

The phrase "largely mediated by" is used to indicate that something is primarily influenced or caused by a specific factor. For example: "The effect of the drug was largely mediated by its interaction with specific receptors."

What are some alternatives to "largely mediated by"?

You can use alternatives such as "primarily influenced by", "mainly driven by", or "substantially governed by" depending on the context.

Is it correct to say "partially mediated by" instead of "largely mediated by"?

Yes, "partially mediated by" is correct when the influence of a factor is not the primary one but still significant. "Largely mediated by" implies a greater degree of influence.

What is the difference between "mediated by" and "largely mediated by"?

"Mediated by" indicates that something is facilitated or caused by a specific factor, while "largely mediated by" emphasizes that the factor is the principal, but not necessarily the only, cause or facilitator.