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Exact(5)
In both arms, the subjects were administered a PA dose consistent with the label dosing utilized clinically; the dose was administered once daily for three consecutive days.
Spatial heterogeneity with respect to the label concentration throughout the organism, temporal variations due to label dosing over weeks, as well as the stochasticity inherent to biochemical processes, may cause varying label uptake in cells [ 1].
Therapeutic dose range for atypical antipsychotics was also calculated based on the FDA label dosing recommendations.
Reintroduction of a new „rescue" ABT scheme – meropenem + tigecycline + colimycin, with microbiologic control proving the off- label dosing.
The use of qualitative methods such as focus groups or interviews would further explore the reasons for why pharmacists were requesting information on doses, perhaps for off label dosing or because they do not trust the information presented.
Similar(55)
The study plan employed randomized, open label, dose escalation design.
An evaluation of 10percentand20percentcent benzocaine gels in patients with acute toothaches: efficacy, tolerability and compliance with label dose administration directions.
In all studies, cats were treated at the minimum label dose to provide 6.0 mg selamectin per kg bodyweight.
This study was designed to characterize pharmacokinetics of major circulating Danshen catechols in human subjects intravenously receiving the injection at the label doses.
The phase 1 component of the study is an open label dose escalation pilot study in which three cohorts of subjects with ARDS receive increasing doses of human MSCs administered as a single intravenous infusion.
This open label, dose-escalation phase I trial describes the first administration of XR5944.
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