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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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it is mediated by

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "it is mediated by" is correct and usable in written English.
You can use it when discussing processes or interactions that involve an intermediary or a facilitator. Example: "The communication between the two parties is mediated by a third-party organization to ensure neutrality."

✓ Grammatically correct

Science

Encyclopedias

News & Media

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

While it would be extreme to suggest that Tuten has no taste for life unless it is mediated by culture, his art is freed into its natural gaiety and nimbleness by the intercession of figments — Mao, Tintin, Van Gogh, characters from "The Magic Mountain," the stylized participants in the French Revolution.

News & Media

The New Yorker

The occasionalist's answer to the question is to show how interaction appears to be direct when in fact it is mediated by the fourth, uncreated Cartesian substance, God.

In the final stages, metamorphosis is usually a rapid process; it is mediated by several hormones produced by the thyroid and pituitary glands.

Instead, it is mediated by an additional Rad52 enzymatic activity that is unique for ssDNA annealing [29, 39, 40].

It is mediated by neutrophils and particularly macrophages, which recognize bacterial pathogens by toll-like receptors (TLRs).

This promoting action was absent in slices from α5(H105R) mice, confirming that it is mediated by the α5-subunit.

It results from absorption of light by the chemical itself or it is mediated by sensitizing or photoinducing chromophores contained in surface waters.

It is mediated by a number of enzymes called DNA methyltransferases (DNMTs), the most important of which are DNMT1, DNMT3a, and DNMT3b.

When all these factors are integrated, it is mediated by signaling through multiple hormones that either promote or inhibit germination (Finkelstein 2004).

It is mediated by synaptic adhesion molecules, and is among the earliest and most indispensable of molecular events occurring during synaptogenesis.

In many systems, it is mediated by lectins present on the surface of the infectious organism that bind to complementary carbohydrates on the surface of the host tissues.

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Expert writing Tips

Best practice

When using "it is mediated by", ensure that the intermediary or influencing factor is clearly identified to avoid ambiguity. For example, instead of saying "The effect is mediated by hormones", specify which hormones are involved.

Common error

While "it is mediated by" is grammatically correct, overuse of passive voice can make writing sound convoluted. Consider rephrasing to use active voice where appropriate for a more direct and engaging style. For example, instead of "The reaction is mediated by enzymes", try "Enzymes mediate the reaction."

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

83%

Authority and reliability

4.5/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "it is mediated by" functions as a verbal phrase in the passive voice. According to Ludwig AI, it indicates that a process or action is carried out through an intermediary or influencing factor. It's frequently used to explain how something happens indirectly.

Expression frequency: Very common

Frequent in

Science

74%

Encyclopedias

5%

News & Media

3%

Less common in

Wiki

2%

Formal & Business

0%

Social Media

0%

Ludwig's WRAP-UP

In summary, the phrase "it is mediated by" is a grammatically correct and commonly used expression, particularly in scientific and academic writing. According to Ludwig AI, the phrase functions to explain that something happens through an intermediary factor. While widely accepted, being mindful of potential overuse of passive voice and clarifying the acting intermediary are recommended best practices. Alternative phrases like "it is facilitated by" may be more appropriate in certain contexts. Its high frequency in scientific publications confirms its usefulness in technical communication.

FAQs

How can I use "it is mediated by" in a sentence?

Use "it is mediated by" to show that a process or effect happens through an intermediary. For instance, "The immune response "it is mediated by" T cells."

What are some alternatives to "it is mediated by"?

You can use phrases like "it is facilitated by", "it is influenced by", or "it is enabled by" depending on the specific context.

What is the difference between "it is mediated by" and "it is caused by"?

"It is caused by" indicates a direct cause-and-effect relationship, while ""it is mediated by"" suggests an indirect relationship where something acts as an intermediary or facilitator.

Is it better to use active or passive voice with "it is mediated by"?

While ""it is mediated by"" is in passive voice and grammatically correct, using active voice can sometimes make the sentence more direct and easier to understand. For example, you can rephrase "The process "it is mediated by" enzymes" as "Enzymes mediate the process."

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Most frequent sentences: