it is demonstrated to mediate

USAGE SUMMARY

The phrase "it is demonstrated to mediate" is correct and usable in written English.
You can use it in contexts where you are discussing research findings or evidence that shows a particular factor or variable plays a mediating role in a relationship between other variables. Example: "The study found that social support is demonstrated to mediate the effects of stress on mental health outcomes."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

1 human-written examples

It is demonstrated to mediate the immediate and delayed inflammatory responses of vascular endothelial cells.

Behavioral and Brain Functions

Human-verified similar examples from authoritative sources

Similar Expressions

59 human-written examples

Furthermore, bradykinin has been demonstrated to mediate its anti-arrhythmic effects through liberation of NO during I/R (Vegh and Parratt 2005).

Dose-Response

The ILK, which was discovered through its interactions with the β1 integrin subunit (Hannigan et al, 1996), has been demonstrated to mediate a plethora of biological events.

British Journal of Cancer

Both IRESes had been demonstrated to mediate bi-cistronic gene expression in baculovirus-infected Sf21 cell.

Journal of the Taiwan Institute of Chemical Engineers

Conversely, S214L mutation exhibited sharply diminished biotin-As binding (Fig. 1D and 1E), similar to the mutant C212A which has been demonstrated to mediate the direct arsenic binding (Jeanne et al., 2010).

Protein & Cell

The modfied Scl2 proteins have been demonstrated to mediate differential endothelial cell (EC) and smooth muscle cell (SMC) adhesion via these integrins and to retain the non-platelet aggregating properties of the "parent" Scl2.

Acta Biomaterialia

In contrast, MUC16 has also been demonstrated to mediate cell adhesion by binding to other cell surface glycoproteins such as galectin-1 and mesothelin [14], [15].

Plosone

Moreover, elevated expression of Osx, which was directly repressed by p53, was demonstrated to mediate the effect of p53 on differentiation.

Plosone

LL-37, the proteolytically (proteinase 3) active product of hCAP-18, has been demonstrated to mediate a wide variety of immune and inflammatory functions, including wound repair.

Plosone

The nuclear export components CRM1 (chromosome region maintenance 1) and exportin 4 were demonstrated to mediate the nuclear export of Smad proteins [33] [35].

Plosone

Adoptively transferred tumor antigen-specific CD4+ T cells have been demonstrated to mediate dormancy or regression of tumors [12], [16], [21], even eradication of large established tumor masses was observed [11], [13], [14].

Plosone

Expert writing Tips

Best practice

When using "it is demonstrated to mediate", clearly state what "it" refers to and what process is being mediated. Providing specific examples or data strengthens the statement.

Common error

Avoid using "it is demonstrated to mediate" without sufficient evidence. Ensure the claim is supported by research findings and not based on speculation or preliminary data.

Linguistic Context

The phrase "it is demonstrated to mediate" functions as a declarative statement asserting that something has been proven to act as an intermediary or mechanism. This is typically used to explain a process or relationship, as evidenced by the Ludwig examples.

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, the phrase "it is demonstrated to mediate" is a formal and scientific way of stating that something has been proven to act as an intermediary in a process or relationship. Ludwig AI analysis indicates that this phrase is grammatically correct and most commonly found in scientific contexts. Although acceptable, it is relatively rare. When using this phrase, ensure that there is sufficient evidence to support the claim and clearly identify what "it" refers to. Consider using more common alternatives such as "it has been shown to mediate" for broader audiences.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

it has been shown to mediate

Uses a more common passive voice construction.

it is proven to mediate

Emphasizes the certainty of the mediating effect.

it is found to mediate

Focuses on the discovery aspect of the mediation.

it is established to mediate

Highlights the well-established nature of the mediation.

evidence suggests it mediates

Shifts the emphasis to the suggestive nature of the evidence.

the data indicates it mediates

Focuses on the data as the basis for the mediation.

research demonstrates its mediating role

Rephrases to emphasize the role instead of the action.

studies reveal its mediation

Transforms the verb into a noun phrase.

it is understood to be a mediator

Emphasizes understanding and the role of a mediator.

the mechanism is shown to be through

Focuses on the mechanism of action.

FAQs

What does "it is demonstrated to mediate" mean?

The phrase "it is demonstrated to mediate" means that evidence or research has shown that something plays a key role in connecting or influencing a process or relationship between two or more things.

How can I use "it is demonstrated to mediate" in a sentence?

You can use "it is demonstrated to mediate" to explain a mechanism by which one factor affects another, for example, "Social support "it is demonstrated to mediate" the effects of stress on mental health".

What can I say instead of "it is demonstrated to mediate"?

You can use alternatives like "it has been shown to mediate", "it is proven to mediate", or "it is found to mediate" depending on the context.

Is "it is demonstrated to mediate" formal or informal?

"It is demonstrated to mediate" is generally considered a formal phrase, suitable for academic and scientific writing. More informal alternatives might include "it helps" or "it plays a role".