is upregulated by

USAGE SUMMARY

The phrase "is upregulated by" is correct and usable in written English.
It is typically used in scientific or technical contexts to describe a process where the expression of a gene or protein is increased by a specific factor or condition. Example: "The expression of the gene is upregulated by the presence of the hormone."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

Recent studies have shown that TM expression is upregulated by several NRs.

European Journal of Pharmacology

The OsRERJ1 gene is upregulated by JA (Kiribuchi et al. 2004).

Rice

These data suggest that AIF is expressed in HCAECs and is upregulated by ox-LDL.

Biochemical and Biophysical Research Communications

Its expression is upregulated by activated endothelium under inflammation, unlike resting endothelial cells [8].

Clinical and Translational Medicine

Results The secretion of Endocan by HUVECs is upregulated by LPS and poly (I C).

Annals of Intensive Care

CREB is upregulated by chronic antidepressant treatment, and increasing CREB levels in rodent models results in antidepressant-like behaviors.

Biological Psychiatry

Concordantly, beta-amylase, BMY7, is upregulated by both treatments.

Plosone

Moreover, SGK-1 itself, is upregulated by cAMP.

Plosone

Tetherin is upregulated by IFNα and inhibits the release of newly assembled virions in cell lines.

Plosone

Its expression is upregulated by probacteria and bacterial products such as lipopolysacharide and sodium butyrate.

Plosone

Expression of neurotrophic factors (BDNF, VEGF and VGF) is upregulated by environmental enrichment [16], [23], [24].

Plosone

Expert writing Tips

Best practice

When writing scientific content, remember that the phrase "is upregulated by" is most appropriate when you wish to describe an increase in gene expression or the number of cell receptors. Use more general terms like "is increased by" in other contexts.

Common error

Avoid using "is upregulated by" in general writing. This phrase is specific to scientific and technical discussions, particularly in biology and medicine. Using it outside these contexts can sound unnatural or pretentious. Instead, use "is increased by" or "is enhanced by" in common writing.

Linguistic Context

The phrase "is upregulated by" functions as a passive construction in scientific writing, indicating that the expression of a gene, protein, or other biological factor is increased by a specific stimulus. This is supported by the examples provided by Ludwig, which come primarily from scientific sources.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, the phrase "is upregulated by" is a grammatically correct and highly prevalent expression, particularly within scientific literature. According to Ludwig, this phrase is used to denote that the expression of a gene or protein is increased due to a specific factor or condition. Due to its technical nature, it's best suited for formal, scientific contexts. In more general writing, alternatives like "is increased by" or "is enhanced by" might be more appropriate. While Ludwig AI confirms the validity and usability of the phrase, understanding its specific context ensures effective and accurate communication.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

is enhanced by

Suggests an increase in effectiveness or quality, subtly different from direct quantity.

is stimulated by

Implies an activation or encouragement of a process by a specific factor.

is increased by

Focuses directly on the rise in quantity or intensity caused by something.

is promoted by

Suggests the process or expression is being advanced or supported by a specific factor.

is activated by

Emphasizes the initiation or triggering of a process due to a specific cause.

is amplified by

Implies an increase in magnitude or intensity, often used in technical contexts.

is augmented by

Suggests something is added to increase its effect or quality.

is induced by

Focuses on the causing or bringing about of a process or state.

shows increased expression due to

A longer, more descriptive alternative focusing on gene expression change.

experiences elevated levels due to

Highlights the raised levels as a result of a certain condition or substance.

FAQs

How is "is upregulated by" used in scientific writing?

In scientific writing, "is upregulated by" indicates that a gene, protein, or other biological factor's expression or activity is increased due to a specific stimulus or condition. For example, "Gene X is upregulated by hypoxia" means Gene X's activity increases when oxygen levels are low.

What are some common synonyms for "is upregulated by" in scientific literature?

Common synonyms include "is increased by", "is enhanced by", "is stimulated by", or "is induced by". The best choice depends on the specific nuance you want to convey.

Is it appropriate to use "is upregulated by" in everyday conversation?

No, the term "is upregulated by" is highly technical and best reserved for scientific or medical contexts. In everyday conversation, use simpler terms like "is increased by" or "is boosted by" for clarity.

What's the difference between "is upregulated by" and "is expressed by"?

"Is expressed by" refers to the production or presence of a gene or protein. "Is upregulated by" means that the level of expression or activity of that gene or protein is increased by a particular factor. So, a gene "is expressed by" a cell, and its expression "is upregulated by" a certain condition.