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The phrase "is insignificant to" is correct and can be used in written English.
This phrase is used when comparing two objects or concepts in order to indicate a lack of importance. Example: The minor issue of clutter is insignificant to the much larger, more significant problem of global warming.
Dictionary
is insignificant to
adjective
Not significant; not important, consequential, or having a noticeable effect.
synonyms
Exact(8)
Planes and everything is insignificant to what Rio and his family are going through.
On one hand, the big thing that just happened to you is insignificant to the rest of creation, and on the other, you are still part of a creation that's so much bigger than your loss.
The premise of the episode is that Ben has gotten a job in Washington with a congressman, and Leslie begins to feel that she is insignificant to the functioning of American democracy.
It is insignificant to claim the robustness without taking FPR into consideration.
However, the overall impact of the polymer concentration × shear rate is insignificant to the viscosity.
While the code examples use line breaks and indentation for clarity, this is not required; whitespace is insignificant to chemfig.
Similar(52)
My suffering was insignificant to his pleasure.
"It may also not be insignificant to the child".
I said, "It might be insignificant to you, mate.
Sights are insignificant to Hage; what matters are people and their stories.
The dams' 1,000 megawatts of generation are insignificant to making climate progress.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com