Sentence examples for irrespective of functional from inspiring English sources

Spreading depression (SD) is an intense self-propagating wave of depolarization involving neuronal and glial cells in the cerebral cortex, subcortical gray matter or retina, irrespective of functional divisions or arterial territories.

The large size of these data sets may reflect the inherent limitations of genome-wide ChIP because it identifies DNA sites irrespective of functional significance.

In each case, the distribution within the functional category was compared to the distribution for the total gene set, including the genes within the functional category, to test the null hypothesis that the observed distribution of expression changes affected all genes irrespective of functional category.

It should be mentioned that a target site was regarded to be gained by both substitutions and indels if the ancestral sequence before it became a target site could not be estimated due to the absence of orthologous target sites (irrespective of functional or nonfunctional) in the outgroup Drosophila species; more than half of gains grouped as "both" were classified in this category.

gambiae irrespective of the functional group analysed, with an average of 79.35% similarity between the two anopheline species (Table 5).

Unlike agr, mutation of sarA was found to limit biofilm formation in all USA300 isolates irrespective of the functional status of agr (Fig. 4).

In contrast, mutation of sarA resulted in a reduced capacity to form a biofilm in all clinical isolates irrespective of the functional status of agr.

However, these are extrapolations and in contrast to our study they included tumors from different origins and examined all somatic mutations irrespective of their functional relevance.

Given its high level of protease production by comparison to clinical isolates, one possible explanation for this is that the increased production of extracellular proteases also limits nuclease activity in RN6390 irrespective of the functional status of sarA.

Using MitoTracker green (Molecular Probes, USA), which labels mitochondria irrespective of their functional status, we found that DJ-1 KO cells showed a significantly higher fluorescent signal than WT controls (Fig. 8A).

The same inverse relationships were also observed in UAMS-1 and all three of the USA300 isolates we examined, the difference being that the impact of sarA was evident in these strains irrespective of the functional status of agr (Fig. 6).