Sentence examples for inhibit activity from inspiring English sources

It was shown that the BRCA1 protein binds to ERα to inhibit activity of the activation function AF-2 domain and may cause conformational change and recruitment of coactivator proteins [ 27].

The target gene itself can be altered by mutation or amplification, thus limiting the ability of the drug to inhibit activity of the kinase that remains active and drives aberrant signaling.

In this study, we first used the IκB EGFP protein as an indicator to screen microbial metabolites and demonstrated that the effective substance selected from the screening system can inhibit activity of NF-κB by inhibition of IκB degradation.

As well as decreasing pro-inflammatory cytotrafficking (cytokines and NO synthesis) [ 10], acidification and phosphorylation and, in consequence, activation of proteolytic enzymes, TLN can also inhibit activity of MMPs [ 45].

The difference between rod and cone vision in this respect probably resides in the power of the eye to inhibit activity in cones rapidly, so that the sensation evoked by a single flash is cut off immediately, and this leaves the eye ready to respond to the next stimulus.

Both carbon monoxide and zinc inhibit activity to a considerable extent.

The concentration required to inhibit activity of the enzyme by 50%% (IC50) was calculated by regression analysis [33].

It was recognized to inhibit activity of kinases such as Bcr/Abl, platelet-derived growth factor receptor, and c-kit.

Several β-mannanases from Streptomyces strains (Kumagai et al. 2013) and Cellulosimicrobium sp. (Kim et al. 2011) had a similar tendency to inhibit activity with Zn2+ ion.

Perturbation at any level of these structures can have a significant role in determining domain accessibility which can either improve or inhibit activity in that region.

It has been reported that green tea and decaffeinated green tea also inhibit activity of H1299 human lung carcinoma cell line.