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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
increased twofold in
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "increased twofold in" is correct and usable in written English.
It can be used to describe a situation where a quantity has doubled in size, amount, or degree compared to a previous measurement or state. Example: "The company's profits increased twofold in the last quarter, reflecting a significant improvement in sales."
✓ Grammatically correct
Science
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
36 human-written examples
A recent meta-analysis (15,877 subjects, 17 studies, average follow-up of 7.7 years) has shown that the risk of cardiovascular events is increased twofold in patients with increased PWV [ 20].
Mortality is increased twofold in patients with AF.
Science
By immunonprecipitating DAXX from nuclear protein extracts of Pten-wt and Pten-null MEF (mouse embryonic fibroblast) cells we observed that the levels of H3.3 that co-immunoprecipitated with DAXX increased twofold in Pten-null cells when compared with Pten-wt cells (Fig. 2d, left panel and Supplementary Fig. 1e).
Science & Research
We determined that in a segment of the IAP promoter between −378 and −303 base-pairs upstream from the transcriptional start site, the acetylation state of histone H3 increased twofold in the differentiated, IAP expressing cells, whereas that of histone H4 remained essentially constant.
Adult human bone marrow-derived stem cells (hBMSC) encapsulated in such hydrogels at chitosan/collagen ratios of 100/0, 65/35, 25/75, and 0/100 wt% exhibited high viability at day 1 after encapsulation, but DNA content dropped by about half over 12 days in pure chitosan materials while it increased twofold in materials containing collagen.
Science
The CTC metabolite iso-chlortetracycline increased twofold in concentration.
Human-verified similar examples from authoritative sources
Similar Expressions
24 human-written examples
This number increases twofold in patients who are admitted to the medical ward [14].
Postmenopausal breast cancer risk increases twofold in women who gain significant amounts of weight [ 1] and there is evidence that energy restriction may reduce risk [ 2].
Science
One caveat is that GAPDH levels typically increase twofold in murine cells transformed with v-Src [ 30, 36], a finding consistent throughout the current study, and this was factored into the final normalization.
Science
The plasma FFA15 levels increased twofold to threefold in comparison with the FFA0 levels.
Science
Furthermore, the risk of CV death is increased twofold to fourfold in people with T2D.
Science
Expert writing Tips
Best practice
When using the phrase "increased twofold in", ensure that the context clearly establishes the baseline or original value against which the increase is measured.
Common error
Avoid using "increased twofold in" without clearly defining what is being doubled, as ambiguity can lead to misinterpretations. Always specify the initial value or reference point to ensure clarity.
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "increased twofold in" typically functions as a descriptive modifier, indicating the extent of an increase within a specific context. Ludwig AI provides several examples where this phrase quantifies changes in scientific and medical research.
Frequent in
Science
95%
Academia
3%
News & Media
2%
Less common in
Formal & Business
0%
Encyclopedias
0%
Wiki
0%
Ludwig's WRAP-UP
In summary, the phrase "increased twofold in" is a grammatically correct and frequently used expression, primarily in scientific and academic writing, to describe a 100% increase or doubling. Ludwig AI's analysis confirms its common usage and provides various examples demonstrating its application across different research contexts. While simpler alternatives like "doubled" exist, "increased twofold in" offers precision suitable for formal settings. When employing this phrase, clarity in defining the baseline value is crucial to avoid ambiguity.
More alternative expressions(10)
Phrases that express similar concepts, ordered by semantic similarity:
doubled in
Direct synonym indicating multiplication by two.
increased by 100% in
Expresses the same concept using a percentage increase.
multiplied by two in
More explicit about the mathematical operation.
grew twofold in
Uses "grew" as a verb, implying an increase.
experienced a twofold increase in
Adds a bit more formality, emphasizing the increase itself.
saw a doubling in
Focuses on the "doubling" aspect of the change.
increased by a factor of two in
Specifies the factor of increase.
rose by twofold in
Uses "rose" as a verb, similar to "grew".
became twice as large in
Describes the end result of the increase.
expanded twofold in
Implies an enlargement or widening.
FAQs
What does "increased twofold in" mean?
The phrase "increased twofold in" means that something has doubled in quantity, size, or degree. It indicates a 100% increase relative to the original value.
How can I use "increased twofold in" in a sentence?
You can use "increased twofold in" to describe changes in data, statistics, or experimental results. For example, "The concentration of the substance "increased twofold in" the second sample."
What are some alternatives to saying "increased twofold in"?
Alternatives to "increased twofold in" include "doubled in", "increased by 100% in", or "multiplied by two in". The best choice depends on the specific context.
Is it better to say "increased twofold" or "doubled"?
Both "increased twofold" and "doubled" are correct and often interchangeable. "Doubled" is generally simpler and more direct, while "increased twofold" might be preferred in formal or scientific writing for its precision.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested