"With the new millennia, new technology and new ways to treat patients, administrations are trying to reconfigure services geared to an increased aging population, and -- even more pressing -- emergency rooms that are more overcrowded than ever in history," Mr. Sisto said.
The reason I call myself a stress reductionist, is because I know how important stress is and the effects it has on our bodies; increased aging, disease provoking, illness enhancing.
Whilst our data are consistent with the notion that early inflammation leads to increased aging mediated by innate responses, the question remains if this observation relates also to vertebrates.
The increased aging of the population is a consideration, but increased risk factors across all age groups limit aging as a sole explanation [ 3].
First, oxidative stress has been associated with increased aging at the molecular level as shown by the deletion of the superoxide dismutase 1 (Sod1) gene producing a decrease in the lifespan of mice [ 27].
It also raises the question whether combating Myc- and Myc/Ras-driven tumors with Cdk2-inhibitors comes with the side-effects of stem cell failure, decreased regeneration capacity in normal tissues and increased aging?
