Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
in the initial sequence
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "in the initial sequence" is correct and usable in written English. You can use it when referring to the first part of a series or order of items, events, or steps. For example, "The results were consistent with those found in the initial sequence of experiments." Alternative expressions include "in the first sequence" and "in the primary sequence."
✓ Grammatically correct
Science
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
4 human-written examples
In such approaches, errors in the initial sequence alignment might be identified subject to two conditions.
Science
An important finding of this study is that for all four BACs, 454 sequencing technology provided an excellent coverage of all gene containing fractions already in the initial sequence assemblies.
Science
Binding sites present in the initial sequence are expected to reduce time-to-evolve only if they are for the right TFs, that is, ones that can contribute to the target pattern.
Science
There were four sets of reads used in the assembly: (i) Merged reads, including MiSeq PET 500 bp libraries and HiSeq PET 250 bp, and (ii) HiSeq PET 500 reads were used in the initial sequence assembly.
Science
Human-verified similar examples from authoritative sources
Similar Expressions
56 human-written examples
In brief, the initial sequence had substitutions introduced at each position with a probability derived from a uniform probability distribution.
Science
The problem is that, at least in the initial sequences set in Bilbo's home of Bag End (Middle Earth's equivalent to the Home Counties), the effect is kitsch and alienating.
News & Media
While not all the financing is in place, the French government has pledged to cover Genoscope's participation in the initial sequencing.
Science & Research
Joining Celera in the initial sequencing will be France's Genoscope sequencing center in the Paris suburb of Evry, which earlier this year received a $3.5 million grant from the French government for its part of the work.
Science & Research
Both the degree of diversity in the initial sequences and the cluster density on the flowcell impacts the extent of data loss.
Science
Finally, genomic regions containing simA and scpI were resequenced using standard BigDye sequencing techniques (Eton Bioscience Inc). to confirm data generated in the initial sequencing efforts.
Science
The discrepancies are due to the different number of glutamines in the polyglutamine region of exon 1 that were reported in the initial sequences of AR.
Science
Expert writing Tips
Best practice
When using "in the initial sequence", ensure the context clearly establishes that a series of steps or events is involved. Avoid using it when referring to a single, isolated event.
Common error
Avoid using "in the initial sequence" when you simply mean "at the beginning" if there isn't a clear series or process involved. Choose simpler alternatives like "initially" or "at the start" when the sequential aspect isn't relevant.
Source & Trust
78%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "in the initial sequence" functions as a prepositional phrase, modifying a noun or verb by specifying the location or time frame within a series of events or steps. Ludwig examples show its use in contexts like sequence alignment or data processing.
Frequent in
Science
80%
News & Media
10%
Formal & Business
10%
Less common in
Encyclopedias
0%
Wiki
0%
Reference
0%
Ludwig's WRAP-UP
The phrase "in the initial sequence" is a prepositional phrase primarily used to specify the beginning stages of a process or a series of events. As shown by Ludwig, it is most frequently found in scientific and technical contexts, which contributes to its formal register. Alternatives include phrases like "at the beginning" or "in the early stages", although these may lack the specific connotation of a structured order. The use of this phrase implies that the context involves a defined series of steps, and it should be avoided in situations where a simpler term like "initially" would suffice.
More alternative expressions(10)
Phrases that express similar concepts, ordered by semantic similarity:
in the first stage
Specifically identifies the primary step, similar to the original phrase.
at the beginning
Highlights the early phase, without necessarily implying a structured series of events.
in the opening sequence
Refers to the introductory part, commonly used in narrative or procedural contexts.
at the start
Focuses on the commencement point, omitting specific reference to an ordered set.
in the preliminary phase
Stresses the preparatory aspect of the beginning.
in the early stages
Emphasizes the developmental phase rather than a strict sequential order.
at the outset
Implies the very beginning, carrying a more formal tone than the original phrase.
initially
A single-word adverb conveying the idea of the first action or state.
in the foundational sequence
Highlights the base or groundwork of a process.
to begin with
Indicates the starting point, used mainly to introduce arguments or steps.
FAQs
How can I use "in the initial sequence" in a sentence?
Use "in the initial sequence" to refer to the starting point of a process or ordered series of events. For example, "Errors were identified "in the initial sequence" of the alignment process."
What are some alternatives to "in the initial sequence"?
Alternatives include "at the beginning", "in the early stages", or "at the start", depending on the specific context and the nuance you wish to convey.
Is it more appropriate to say "in the initial sequence" or "at the initial sequence"?
"In the initial sequence" is generally more appropriate and grammatically correct. "At the initial sequence" is less common and might sound awkward to native English speakers.
What's the difference between "in the initial sequence" and "initially"?
"In the initial sequence" refers specifically to the beginning of a structured series, whereas "initially" simply means 'at first' and does not necessarily imply a sequence.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
78%
Authority and reliability
4.1/5
Expert rating
Real-world application tested