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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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in spite of their differences

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "in spite of their differences" is correct and usable in written English.
You can use it to indicate that something occurs or is true despite the differences between people, groups, or things. Example: "They managed to work together effectively in spite of their differences."

✓ Grammatically correct

News & Media

Science

Encyclopedias

Human-verified examples from authoritative sources

Exact Expressions

44 human-written examples

In spite of their differences in the route of effective administration, KTP-NH2 and KTP differ structurally only by the amidation.

This creates commonalities between actors, in spite of their differences.

News & Media

The Guardian

Others will feel duty-bound to serve as shadow ministers in spite of their differences.

In spite of their differences, however, Charles I and Cromwell shared a belief in their religious purpose, Ackroyd argues.

News & Media

Independent

Through active diplomacy, he persuaded his fellow mujahedeen to stand by Mr. Karzai in spite of their differences.

News & Media

The New York Times

In an interview, Katrina vanden Heuvel, editor of The Nation, said that in spite of their differences over political issues, she was unhappy with Mr. Hitchens's decision.

News & Media

The New York Times
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Human-verified similar examples from authoritative sources

Similar Expressions

16 human-written examples

They've exchanged letters, and in spite of their difference in age and location (Amy is an old lady, Sara a woman in her 20s) they have bonded over books.

News & Media

Independent

The very similar values for the PEA and PS ionomers, in spite of their difference in matrix Tgs themselves, led to a postulation that the PEA ionomers have bigger multiplets and longer persistence length than the PS ionomers.

Science

Polymer

In the heat map, all methanogenic archaea, in spite of their difference in genomic GC content and habitat, show an affinity for higher usage of Cys residues in their proteomes as compared to sulphur-metabolising counterparts.

The two subspecies have been considered to be very close relatives that could be distinguished only by minute differences in vitro in spite of their marked differences of physiology in vivo.

The present data show that the three PB1-F2 peptides from IAV of different pahtogenic potential have in spite of their sequence differences the same ability to generate ion channel activity.

Science

Plosone
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Expert writing Tips

Best practice

When using "in spite of their differences", ensure that the sentence clearly demonstrates how those differences are being overcome or disregarded to achieve a common goal or maintain a relationship.

Common error

Avoid using "in spite of their differences" when the differences are actually the cause of a negative outcome. The phrase implies that something positive or neutral occurs despite the differences, not because of them.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

84%

Authority and reliability

4.5/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "in spite of their differences" functions as a prepositional phrase that introduces a clause of concession. It highlights a contrast, indicating that something is true or happens even though there are differences present. Ludwig AI shows its prevalent usage across various contexts.

Expression frequency: Very common

Frequent in

News & Media

50%

Science

33%

Encyclopedias

8%

Less common in

Wiki

2%

Reference

2%

Formal & Business

2%

Ludwig's WRAP-UP

The phrase "in spite of their differences" is a grammatically sound and frequently used prepositional phrase that introduces a clause of concession. According to Ludwig AI, this phrase serves to emphasize resilience or cooperation that occurs despite existing disparities, often highlighting a noteworthy outcome. Although versatile, it is most commonly found in News & Media and Science contexts, with a neutral to formal register. Closely related alternatives include "despite their differences" and "regardless of their differences". Ensure that the phrase is used when differences exist but don't impede a positive or neutral outcome.

FAQs

How can I use "in spite of their differences" in a sentence?

Use "in spite of their differences" to show that a particular outcome is achieved or a relationship is maintained even though there are differences between the entities involved. For example, "They cooperated effectively "in spite of their differences"".

What phrases are similar to "in spite of their differences"?

Is there a difference between "in spite of their differences" and "despite their differences"?

The phrases "in spite of their differences" and "despite their differences" are largely interchangeable and carry the same meaning. "Despite" is often considered more concise and is slightly more common in modern usage.

When should I avoid using "in spite of their differences"?

Avoid using "in spite of their differences" if the differences are the direct cause of a negative result. This phrase is used to emphasize that something positive occurs despite existing differences.

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Authority and reliability

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Real-world application tested

Most frequent sentences: