in linkage with

USAGE SUMMARY

The phrase "in linkage with" is not commonly used in written English and may sound awkward to some readers.
It can be used when discussing connections or relationships between two or more entities, but "in connection with" is more standard. Example: "The research findings are in linkage with previous studies on climate change."

Science

Human-verified examples from authoritative sources

Exact Expressions

59 human-written examples

Thus, longer than expected segments of tiger salamander DNA are retained in linkage with tyr a in the laboratory axolotl.

Nature

The majority of albinos in the current AGSC population retain >7 cM of tiger salamander DNA in linkage with tyr a.

Nature

An adequate spatial distribution of hydrological gauging stations presents a lot of interest in linkage with the river regime characterization, water infrastructures design, water resources management and ecological survey.

Journal of Hydrology

The in silico bioinformatics analyses revealed that EGFR rs2072454 and SNPs in linkage with the identified SNPs in MET and ALDH1A1 (r2 > 0.6) were predicted to regulate RNA splicing.

Duke University

The MHC microsatellites used here are known to be in linkage with MHC Class I, II, and III genes [67].

Plosone

In the first stage, microsatellites were typed in the 17q11.2 region, previously independently found to be in linkage with MS. One significant association was found at microsatellite D17S798.

Plosone

Because the nonMHC loci were highly polymorphic, they are likely to be in linkage with nearby functional loci under balancing selection [68], [69].

Plosone

Although we measured genetic diversity using microsatellites assumed to be selectively neutral, the MHC markers used here are known to be in linkage with MHC genes [67].

Plosone

It is also interesting to note that in humans, the −1030 T/C SNP occurs in linkage with the −862 C/A SNP [16], [19], [29], [67] [69].

Plosone

In addition, the nonMHC markers were highly polymorphic and therefore likely to be in linkage with functional loci under balancing selection [e.g. 68], [69].

Plosone

Indeed, since as described above, the majority of human TNF promoter SNPs have been found to be in linkage with HLA molecules [16], [17], [19], [21], SNPs may also be in linkage with other genes in the MHC locus with functional effects upon resistance and susceptibility to infectious disease.

Plosone

Expert writing Tips

Best practice

When using "in linkage with", ensure the context clearly indicates a genetic or close relationship between the entities being described.

Common error

Avoid using "in linkage with" in contexts where a simpler phrase like "related to" or "associated with" would be more appropriate and widely understood. It is more specific to genetic contexts.

Linguistic Context

The phrase "in linkage with" functions as a prepositional phrase, typically modifying a noun or noun phrase. It indicates a close association or relationship, particularly in genetics, where it signifies that genes are inherited together due to their proximity on a chromosome. Ludwig provides numerous examples in scientific literature.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

The phrase "in linkage with" is a prepositional phrase indicating a close association, particularly in genetics where it describes genes inherited together. Ludwig AI identifies its usage as acceptable, predominantly in formal and scientific contexts. While grammatically sound, simpler alternatives like "associated with" or "related to" might be more suitable in non-scientific contexts. It's crucial to reserve "in linkage with" for scenarios where a genetic or very close relationship is intended, avoiding overuse in general contexts. As Ludwig AI also suggests, it is important to ensure that the context clearly indicates the type of relationship being described.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

associated with

This alternative is more direct and commonly used to indicate a relationship between two things.

linked to

This is a closer synonym, implying a connection or association, but slightly less formal.

connected to

This suggests a physical or logical connection, often implying a direct link.

in association with

This alternative is more formal and emphasizes the combined or cooperative nature of the connection.

related to

This indicates a general relationship or association, without specifying the nature of the connection.

tied to

This indicates a strong and often inseparable connection or dependency.

correlated with

This suggests a statistical relationship, where changes in one variable are associated with changes in another.

bound to

Suggests a strong and inevitable connection or obligation.

dependent on

This indicates that one thing relies on another.

in relation to

This is a more general term indicating a connection or relevance between two or more things.

FAQs

What does "in linkage with" mean?

In genetics, "in linkage with" describes the phenomenon where two or more genes tend to be inherited together because they are located close to one another on the same chromosome. It can also be used more generally to describe a close association or relationship between two entities.

When is it appropriate to use "in linkage with"?

Use "in linkage with" when discussing genetic relationships, such as genes inherited together. In other contexts, consider using alternatives like "associated with", "connected to", or "related to" for broader applicability.

How can I use "in linkage with" in a sentence?

Example: "The majority of albinos in the current AGSC population retain >7 cM of tiger salamander DNA in linkage with tyr a."

Are there any common phrases similar to "in linkage with"?

Yes, some common phrases with similar meanings include "associated with", "connected to" and "related to". The best choice depends on the specific context and the nature of the relationship you want to convey.