hold step

USAGE SUMMARY

The phrase "hold step" could be correct and usable in certain contexts in written English, but it would likely need to be modified or expanded to make sense.
As it stands, "hold step" does not convey a clear meaning or grammatical structure. Possible ways to use this phrase could include: - As part of a longer phrase, such as "hold step by step," to describe a careful or deliberate approach to a task or situation: "We need to take a hold step by step to properly address this issue." - As a command or instruction, such as "Please hold step," to indicate that someone should stop or pause in their actions: "As the music ended, the dancers were instructed to hold step until the next beat." - As a compound noun or adjective, such as "hold-step program" or "hold-step method," to describe a specific approach or strategy being employed: "The company is implementing a new hold-step program to improve efficiency."

✓ Grammatically correct

Science

Wiki

News & Media

Human-verified examples from authoritative sources

Exact Expressions

21 human-written examples

The following PEG driven precipitation and resolubilization of the protein of interest was use to condition the CPC output stream to suit subsequent chromatographic steps, to increase mAb concentration, remove the phase forming polymer, further improve HCP clearance, and integrate a low pH hold step for viral clearance.

Journal of Chromatography A

Algorithm 1 Step 1. Input the matrices A i, A d i, B i, C i, D i and E i, i ∈ N ̲ ; Step 2. By adjusting parameters α and β, we can find the solutions of v i, υ i, ϑ i, ς i, h i such that (43) and (45) hold; Step 3. From h i = K i M ¯ T B i M ¯ T v i and h i = K i M T B i M T v i, one can obtain the gain matrices K i = [ K i M T K i M ¯ T ] T, and then substitute K i into (44) and (46).

Advances in Difference Equations

These enzyme mixtures were then supplemented with twice desalted Cellic® CTec2 from Novozymes (Bagsvaerd, Denmark) after the initial 24-h high temperature hold step.

Biotechnology for Biofuels

We initially used a high temperature enzyme loading of about 15% of the total enzyme loading to test the efficacy of the high temperature hold step at a low solids loading.

Biotechnology for Biofuels

For thermal denaturation, the samples were heated from 20°C to 75°C with stepwise increment of 0.5°C per minute and a 30 s hold step for every point, followed by the fluorescence reading.

BioMed Research International

Employing a higher operating temperature hold step will enable thermophilic enzymes to be added earlier in the process, resulting in both time savings and improved conversion efficiency compared to using current mesophilic, commercial enzyme cocktails.

Biotechnology for Biofuels

Human-verified similar examples from authoritative sources

Similar Expressions

39 human-written examples

We here proposed a new equation in which the holding step was considered.

Journal of Natural Gas Science and Engineering

The authors may estimate the fracture stress intensity factor Upp/Ut incorrectly by ignoring the effect of holding step in indentation load-displacement curves when evaluating the plastic-to-total energy ratio.

Journal of Natural Gas Science and Engineering

We employ the induction principle on time scales (Lemma 1.5) to show that holds step by step.

Advances in Difference Equations

The incubation profile was 16 cycles at 95 °C for 30 s, 50 °C for 60 min and a final holding step at 4 °C for 10 min.

BMC Medical Genomics

The PCR amplification program consisted of an initial holding step of 10 min at 95°C, followed by a two-step cycle of 15 s at 95°C and 1 min at 57°C for 40 cycles.

British Journal of Cancer

Expert writing Tips

Best practice

When describing technical protocols, clearly define the purpose and duration of the "hold step" to ensure reproducibility. Specify relevant parameters such as temperature, pressure, or concentration during the hold.

Common error

Avoid using "hold step" loosely for any kind of pause. Reserve it for situations where maintaining specific conditions during the pause is crucial for the process, like in PCR protocols or manufacturing procedures.

Linguistic Context

The phrase "hold step" functions primarily as a noun phrase, often serving as a technical term within scientific and engineering contexts. Ludwig AI, confirms its use to designate a specific stage or action in a process, indicating a pause or a period of maintaining certain conditions.

Expression frequency: Common

Frequent in

Science

80%

News & Media

10%

Wiki

10%

Less common in

Formal & Business

0%

Encyclopedias

0%

Social Media

0%

Ludwig's WRAP-UP

In summary, "hold step" functions as a noun phrase primarily used within scientific and technical domains. Ludwig's analysis of numerous examples shows that it typically refers to a specific stage in a process where certain conditions are maintained. The phrase carries a formal tone and is mostly used in academic papers, research protocols, and technical documentation. While grammatically correct, it's important to reserve "hold step" for scenarios where maintaining precise conditions is crucial, differentiating it from general pauses or delays. The most common contexts include science, news and media, and wiki sources, with scientific journals being particularly authoritative.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

pause stage

Replaces "step" with "stage", focusing on a broader phase within a procedure.

waiting period

Highlights the temporal aspect of holding, framing it as a duration.

delay phase

Emphasizes the act of delaying as a specific segment.

retention interval

Focuses on maintaining a condition or state for a certain period.

incubation period

Specifies a holding time for development or reaction.

dwell time

Highlights the duration of holding at a specific condition.

resting phase

Indicates a period of inactivity or stabilization within a process.

holding duration

Focuses on the length of time a condition is maintained.

quiescent stage

Suggests a period of inactivity before the next action.

standstill point

Highlights a moment of cessation before further progression.

FAQs

How is "hold step" typically used in scientific writing?

In scientific contexts, "hold step" usually refers to a specific stage in a process where conditions are maintained constant for a set period. Examples include maintaining a temperature during PCR or keeping a solution at a certain pH during a chemical reaction.

What's the difference between a "holding step" and a "hold step"?

While the terms are often interchangeable, "holding step" might emphasize the action of holding, whereas "hold step" functions more as a noun describing a specific part of a procedure. The choice depends on the sentence's structure and emphasis.

When is it appropriate to include a "hold step" in a protocol?

A "hold step" is appropriate when maintaining specific conditions (e.g., temperature, concentration) for a defined duration is critical to the outcome of the process. This is common in PCR, protein purification, and viral clearance procedures.

What are some examples of processes that might include a "hold step"?

Processes that benefit from a "hold step" include PCR (to allow for complete DNA denaturation), protein purification (to allow for viral inactivation at low pH), and material curing (to ensure complete polymerization).