Sentence examples for gross alterations from inspiring English sources

18 Splicing mutations and gross alterations: Splice altering mutations and large deletions/duplications have also been described, and recent data suggest that especially gross alterations affecting the promoter of coding regions may have been underreported, accounting for up to 20% of FAP families.

It describes only those experiments in which a limited number of amino acid residues were altered: gross alterations in protein structure, such as the deletion of hundreds of amino acids are not described.

Changes in biomechanical properties were associated with gross alterations in morphology of the fibers and cell-scaffold interaction.

The change in upstream connections among genes specifying spatial transcriptional state is required for more gross alterations in the form of the subparts of a structure.

Genomic rearrangements in inherited disease and cancer involve gross alterations of chromosomes or large chromosomal regions and can take the form of deletions, duplications, insertions, inversions or translocations.

Using light microscopy, no gross alterations in chorionic structures were observed.

Thus a gross alteration of protein function is unlikely and has been confirmed by these findings.

Nerve cross sections did not show any gross alteration either (data not shown).

Furthermore, we did not observe any gross alteration in maternal behavior in the caffeine treated dams.

These findings suggested that there was no gross alteration in the physiology of β-cells from pBI-cAMP double transgenic mice expressing the cAMP reporter.

The selection is "covert," since the critical data pertain to relative abundance of cDNAs over time rather than to gross alteration of phenotype.