Sentence examples for generalised inflammatory response from inspiring English sources

To confirm that the PID in WT mice treated with LPS was not a reflection of a generalised inflammatory response to LPS, the WT and Tlr4−/− mice were also infused intra-peritoneal with 100 µl vehicle or 100 µg ultrapure LPS (n≥5 per group).

Importantly, ISG15 expression did not correlate with a generalised inflammatory response, suggesting that it is specifically associated with bladder tumours.

This could potentially increase the identification of patients that would benefit from treatment that differentiates a generalised inflammatory response from an infection.

These findings suggest that ISG15 and the subset of correlating inflammation mediators may represent a specific host response to bladder cancer, rather than a generalised inflammatory response.

In this setting, AKI is multifactorial: the bypass circuit changes blood concentration and pulsatility and introduces a blood/circuit interface, which stimulates a generalised inflammatory response including increased catecholamine and free haemoglobin levels.

Finally, as no serum acute-phase protein levels were assessed in this study, we cannot rule out that IL-6 serum levels in this population may merely be associated with a generalised inflammatory response to metastatic disease.

Sepsis, severe sepsis, and septic shock represent progressive stages of the same illness, in which a systemic response to an infection mediated by endogenous mediators leads to a generalised inflammatory reaction in organs remote from the initial insult and eventually to organ dysfunction and/or failure [ 1].

Thus, AT III could improve the microcirculation in the course of a generalised inflammatory reaction.

In line with this, Gene Ontology analysis (GO) highlights a specific transcriptomic remodelling for PGN-O111 B4 PGN-O111 B4ults obtained for PGN-K12 showhereash similaresults a generalised inflammatobtaineding response where multiple forctional classes are related to ribosome biogenesis or cellular metabolism.

Multivariate analysis (PCA) identified three temporally distinct patterns in gene expression data from the liver, lung, and spleen tissue: pulmonary inflammation was rapidly induced, followed by transient induction of a generalised inflammatory and haemostatic response, and initiation of the hepatic acute-phase response.

Thus, a severe systemic inflammatory response proceeds to generalised intravascular inflammation together with shock, organ dysfunction and high mortality [2].