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In the resveratrol study, complement pathways, both classical and alternative, as well as acute inflammatory response, were up-regulated for reasons unknown, although the authors noted that no evidence of widespread inflammatory response was observed.
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Sepsis results in widespread inflammatory responses altering homeostasis.
SIRS and sepsis incite widespread inflammatory responses at tissue and cellular levels altering homeostasis.
suPAR (soluble urokinase-type plasminogen activator receptor) or CD87 is a widespread receptor for inflammatory response.
At present, cis-repression is thought to be unlikely to be responsible for the widespread anti-inflammatory response since it has been observed only at high glucocorticoid concentrations.
The damage incited by the inflammatory response is widespread and has been described as a "pan-endothelial" effect because of the distribution of endothelial tissue in blood vessels throughout the body; this effect appears to explain the systemic nature of sepsis.
PMA induced an inflammatory response and caused widespread neurodegeneration in the brains of 3- and 7-day-old rats.
The systemic inflammatory response syndrome is characterized by widespread endothelial damage caused by persistent inflammation from both infectious and noninfectious stimuli.
The widespread cell death causes an immediate and massive inflammatory response that gradually clears out the injury site, leaving behind sparse tissue with enlarged capillaries.
As the dNLR is mainly derived from the count of neutrophils and lymphocytes, our study also supports the potential of widespread use of this biomarker as a surrogate for inflammatory response.
However, generalized intravascular coagulation, as a generalized inflammatory response, is detrimental to the host, favouring widespread fibrin deposition and altered tissue perfusion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com