The presence of functional tissue together with its effects on cardiac function was evaluated by immunofluorescence, histological assays, and echocardiography.
Upon arrival at their destination, they differentiate into the brain's three main cell types – neurons, astrocytes and oligodendrocytes – then sprout connecting branches to form functional tissue.
A stem cell is one that, when it divides, spins off some offspring that remain as stem cells while others turn into functional tissue.
It is biodegradable, which facilitates the regeneration of natural, functional tissue.
Companies like Organovo, for example, aren't actually engineering the cells, and instead are differentiating and laying them in a way that they can mature and grow in to functional tissue.
This strategy lacks the advantages of acellular scaffolds but have a great theoretical potential of functional tissue regeneration.
Functional tissue engineering offers a great potential for the clinical management of such lesions.
Improving elastic matrix generation is critical to developing functional tissue engineered vascular grafts.
Investigation of mechanotransduction pathways will provide mechanistic insight for improving cell therapies and functional tissue engineering.
Rapid and precise arrangement of cells into functional tissue constructs remains a challenge in tissue engineering.
However, regeneration of a functional tissue or organ has so far remained a challenge.
