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We used the Mev intoxication model of brain stem death [7], [14], [15] to determine the temporal alterations elicited by an intravenous administration of Mev in SAP or HR, and correlated them with the concurrent changes in neuronal functionality, tissue oxygen level, blood flow or temperature in the RVLM.
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While OAG addresses the oral functionality and tissue keratinization, the OMAS and OMI focus on the degree of tissue abrogation.
The additional drug delivery capability from electrospun fibers can further enhance the material's functionality in tissue engineering applications.
Such hybrid material scaffolds may be useful to direct skeletal muscle cellular organization, improve cellular functionality and tissue formation.
In the recent decades, a number of researches have been carried out on the use of biomaterials with in vivo like functionality for tissue engineering applications [8 10].
These results indicate that this chip is useful for engineering 3D cellular constructs with high viability and functionality for tissue engineering.
The printed structure composed of spatial patterning of dual stem cells improves cell-to-cell interactions and differentiation capability and promotes functionality for tissue regeneration.
The incorporation of shape memory into cytocompatible scaffolds is anticipated to facilitate the development, delivery and functionality of tissue engineering scaffolds and the in vitro and in vivo study and application of mechanobiology.
Based on these assumptions, the model demonstrates that proteoglycan digestion at discrete time points during culture as well as culture in a hypertonic medium can improve the functionality of tissue engineered cartilage, while culture in hypotonic solution is detrimental to the apparent mechanical properties of the graft.
While previous studies have focused on the end functionality of tissue constructs, an understanding of the development of neotissue within the self-assembling process remains incomplete.
These results were in stark contrast to the protection of functionality and tissue health observed in +0 h animals that did not receive distal occlusions in addition to pMCAO (Figure 7, left column).
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