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'functional defect' is a correct and usable phrase in written English.
It is typically used to refer to a flaw in the functioning of something, such as an appliance, machine, or even a person. For example, "The car's engine had a functional defect, so we had to take it to the mechanic to repair it."
Exact(60)
The assay was able to detect a functional defect when the defective TP53 and ATM clone compromised around 35%and45%5% of the sample, respectively (Supplementary Figure 3).
There was no functional defect or impairment 3 months after operation.
Conclusions: A functional defect, mainly of the restrictive type, was observed in the majority of asymptomatic patients with SSc.
Inhibition of the LYPD1 gene by siRNA attenuated the anti-angiogenic properties of cardiac fibroblasts, whereas the functional defect was rescued by addition of recombinant LYPD1.
However, a functional defect of the mutated protein has never been ruled out [13], [14].
A functional defect such as vasospasm could also lead to the observed pattern of degeneration.
Multiple sclerosis is associated with a functional defect of natural Treg as we and others have reported [5] [7].
It is not entirely clear which precise functional defect is responsible for the loss of leukemogenic potential.
Apart from the severe developmental disturbance, the observed alterations in mitochondrial organization are interesting and might indicate a functional defect.
Taken together, these findings suggested a functional defect in cellular cholesterol export from vascular SMCs as a potential underlying mechanism.
This functional defect is associated with transcriptional changes in Id1 null HSCs, including the increased expression of p21, a well-established target of Id1 repression [13].
Related(20)
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technical defect
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practical defect
effective defect
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com