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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
freely bound
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "freely bound" is correct and usable in written English.
It can be used in contexts where something is bound or tied in a way that allows for freedom of movement or expression. Example: "The artist's creativity was freely bound by the constraints of the medium, allowing for unique interpretations."
✓ Grammatically correct
Science
News & Media
Alternative expressions(3)
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
2 human-written examples
The peptides are freely bound and released by the ATPase of Hsp70.
The weight loss for the HLC and the scaffolds below 120°C could be attributed to the loss of freely bound water.
Human-verified similar examples from authoritative sources
Similar Expressions
58 human-written examples
In the model, Fj is allowed to phosphorylate either Ft or Ds in proportion to its concentration, and Ft and Ds are then permitted to freely bind at cell edges until they reach equilibrium (see Figure 1A).
Science
The MAB modified LRR domain proteins (3.5 pM) were allowed to freely bind and/or dissociate from their homo-dimer partners by equilibrating them at 30°C for 30 minutes in a 12.5 μl reaction containing 30mM NaOH-HEPES [pH 7.8], 60mM NaCl, 5mM MgCl2, 5% (v/v) glycerol and 0.1mg/ml BSA.
Science
These results are consistent with a two-site mechanism in which one molecule of SR RS2) freely binds outside the active site causing activation of SR ΔRS2) phosphorylation and a second molecule binds in the active site causing inhibition (Scheme 3).
Science
Initially, we constructed a simple one-dimensional computational model, in which Fj activity either promotes Ft binding activity or inhibits Ds binding activity, and in which Ft Ds dimers are then allowed to freely bind at either cell edge until they reach an equilibrium state.
Science
Once activated, Protein C binds to its cofactor, Protein S (either freely circulating or bound to C4b-binding protein), and Activated Protein C inhibits the coagulation factors Va and VIIIa.
Science
The cytosol contains huge numbers of ribosomes freely diffusing or bound to the endoplasmic reticulum, and is the main transit pathway for rRNA en route to the mitochondria or the chloroplast.
Science
The model tracks all ribosomes and transfer RNA (tRNA) molecules in a cell each of which is either freely diffusing or bound to a specific messenger RNA (mRNA) molecule at a specific codon position at any time point (Extended Experimental Procedures).
Science
Since the two steps, the discharge of ions at the electrode and the incorporation of the discharged ions into the crystal lattice, are separated in time and space, an intermediate species exists at the surface, that of relatively loosely bound and freely moving atoms, called adatoms.
Encyclopedias
A query formula Q is a conjunction of literals with some variables X occurring freely (that is, not bound by variables); that is, Q ( X ) = L i 1 ∧ … ∧ L i n.
Science
Expert writing Tips
Best practice
When describing the interaction of molecules or particles, use "freely bound" to indicate a reversible or non-permanent association. This is particularly useful in scientific writing.
Common error
Avoid using "freely bound" when you intend to convey a strong, permanent connection. This phrase implies a degree of independence or reversibility in the binding interaction.
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "freely bound" functions as an adverb-participle construction, modifying a noun to describe the nature of its connection. As Ludwig AI shows, this construction is most commonly used in scientific writing to express the state of being loosely or reversibly connected.
Frequent in
Science
60%
News & Media
20%
Encyclopedias
5%
Less common in
Formal & Business
0%
Social Media
0%
Academia
15%
Ludwig's WRAP-UP
In summary, the phrase "freely bound" is a grammatically correct adverb-participle construction that describes a non-rigid connection, as reinforced by Ludwig AI. Its primary function is descriptive, predominantly within formal, scientific registers. Usage is rare, predominantly found in scientific and academic contexts. When writing, ensure to use this phrase when intending to convey a bond that permits freedom of movement or reversibility. Consider alternatives like "loosely connected" or "flexibly linked" to better match the intended nuance. When the intent is to show a strong permanent connection avoid using the phrase "freely bound"
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
loosely connected
This alternative emphasizes the weak or flexible nature of the connection.
unrestrictedly attached
Focuses on the absence of limitations in the attachment.
flexibly linked
Highlights the adaptability of the connection.
easily combined
Emphasizes the readiness with which the elements can be brought together.
readily associated
Highlights the ease of forming an association.
unimpeded binding
Stresses the lack of obstruction during the binding process.
unfettered connection
Highlights the freedom and lack of restraint in the connection.
loosely tethered
Suggests a light or flexible form of constraint.
independently joined
Emphasizes that the joining occurred without external influence.
spontaneously associated
Highlights the automatic or unplanned nature of the association.
FAQs
How can I use "freely bound" in a sentence?
You can use "freely bound" to describe a state where components are connected but not rigidly fixed, allowing for some movement or exchange. For example: "The peptides are "freely bound" and released by the ATPase of Hsp70."
What are some alternatives to "freely bound"?
Depending on the context, you can use alternatives like "loosely connected", "flexibly linked", or "readily associated" to convey similar meanings.
What does "freely bound" imply about the nature of a connection?
"Freely bound" suggests that the connection is not permanent or rigid, allowing for some degree of independence or movement between the components.
In what fields is the term "freely bound" commonly used?
The term "freely bound" is often used in scientific contexts, particularly in biochemistry and materials science, to describe the interaction of molecules or particles.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested