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The transformation thus enables the disassembled material to flow and fill defects, before the original supramolecular polymer is re-assembled.
In regenerative medicine, hydrogels are employed to fill defects and support the infiltration of cells that can ultimately regenerate tissue.
Hence, tissue engineered cartilage scaffolds should be able to span the thickness of native cartilage to fill defects of all shapes and sizes.
For many applications, an in situ forming scaffold that could completely fill defects with complex geometries, adhere to adjacent tissues and foster cell proliferation would be ideal.
Another advantage of using injectable scaffolds is that they can easily fill defects of various sizes and shapes without any need to fabricate scaffolds of complicated shapes (Hu et al. 2008).
Secondly, PRP may act as a bioactive cell scaffold to fill defects and enhance cartilage regeneration.
Similar(52)
Artzi et al. conducted a comparative experiment of bovine bones and β-TCP to fill defect areas in dogs.
The majority of intraluminal filling defects of the pulmonary artery are secondary to pulmonary thromboembolism.
Intraluminal enhancing filling defects of the pulmonary arteries in these patients may represent metastases.
Three of these HSG examinations identified filling defects, and one was not visible.
Differentiation between blood clots and enhancing filling defects may be possible using subtracted data sets.
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