Under optimal conditions, NAL and DIC were extracted with extraction recoveries of 12.5 and 14.6, respectively, which corresponded to preconcentration factors of 300 and 350, respectively.
Extractions using aqueous methanol resulted in extracts exhibiting both lower extraction recoveries and causing more severe matrix effects [ 9].
The determination of the extraction recoveries was performed by comparing the observed peak areas of bergapten in extracted plasma samples with those of the bergapten in non-processed plasma samples at the same theoretical concentrations.
QC samples extraction recoveries were shown in Table 3.
The extraction recoveries are presented in Table 8.
The recovery and RSD for extraction recoveries of IS were 94.9% and 3.07%, respectively.
The extraction recoveries from urine at three concentration levels are presented in Table 6.
Several key parameters were identified and their effects on precision and extraction recoveries were investigated.
The percentage extraction recoveries and the enrichment factors were found to be reasonably quantitative.
The mean extraction recoveries of analytes and IS from rats plasma were all more than 85.0%.
Extraction recoveries in the range of 7.1 21.6% and satisfactory repeatability (2.1 < CV% < 4.5) were obtained.
