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Consistent with the known role of GTPCH1 in synthesizing BH4, required for the function of AAAHs, GFP reporter constructs show cat-4 expression in identified serotonergic and dopaminergic neurons (where TPH and TH are expressed, respectively), and in the epidermis (where both PAH and AGMO are expressed, see below).
To identify neurons responsible for each behavior, we found it necessary to conduct mosaic analyses to correlate expression in identified neurons with induced behavior.
To confirm the ability of HSV-1 to infect cells at a distance from the infection site, we measured GFP expression in identified motoneurons at different segmental levels.
Here we present the first quantitative, genome-wide analysis of 5hmC, 5-methylcytosine (5mC) and gene expression in identified, terminally differentiated CNS cell types in vivo.
This allows an investigation of the role of putative intrinsic determinants by changing their expression in identified stem cells and assessing its effect at the lineage level in an otherwise normal brain.
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This would still support the utility of mTert-GFP expression in identifying a population responsible, at least in part, for cardiomyocyte development and regeneration.
This study investigates the incidence of MSI in patients from the general population with multiple primary colorectal cancers, and the relevance of MLH1, MSH2 and MSH6 gene expression in identifying those patients who may have HNPCC.
There are successful examples of using expression arrays in identifying genes causally associated with quantitative traits of interest, both in plants and animals [ 50, 51].
In this study, our real-time RT-PCR analysis of gene expression in PBMC identified two possible genes with significant genotype-expression association.
To address this question we studied gene expression in three identified neurons, R2, L7 and L11.
Development, morphogenesis, and differential Otd expression in two identified central brain neuroblast lineages, LALv1 and ALad1.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com