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These results support a role for mdr1 gene expression in determining the response of human breast cancer cells to chemotherapy.
Better data are needed to establish the relative importance of the breadth and level of expression in determining evolutionary rates in passerines.
Further investigations are required to characterize the role of ICAM1 expression in determining the virulence of the T. annulata-infected cell.
Yet to date, there is no prospective study that has explored a possible role of an OSA triggered NF-kappaB-mediated TNF-α-induced IL-6 gene expression in determining glucose tolerance status in obese persons with OSA over time.
The prognostic significance of thrombospondin-1 expression, in determining the risk for recurrence, was studied with both univariate (log rank test) and multivariate (Cox proportional hazards) ways of analysis, separately for each group of patients.
In order to assess the predictive value of endometrial β3 integrin expression in determining which endometriosis patients might benefit from precycle prolonged GnRHa therapy, Surrey and colleagues randomized endometriosis patients either to a 3-month course of GnRHa or to proceeding directly to ovarian stimulation after obtaining endometrial biopsies for β3 integrin [ 40].
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Imaging is particularly helpful in recording temporal and spatial resolution of gene expression in vivo, determining vector distribution, and, ultimately, understanding endogenous gene expression during disease development.
Interestingly, the results revealed high involvement of expression levels of ceRNAs in determining ceRNA regulation.
Possibly, p53 may be another factor in determining MT expression.
This technique allows for high throughput in determining biomarker expression in patients, but also introduces the risk of sampling bias.
As shown in Fig. 2B an approximately 4-fold increase in HNF6 gene expression was determined in FOXA2 siRNA-transfected Caco-2 cell cultures.
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