Exact(3)
This platform has a number of advantages that will facilitate further exploration of pathways governing pancreatic differentiation of hESCs.
In that sense, they are a useful guide to the identification and exploration of pathways involved in a particular process.
An initial exploration of pathways affected shows that some of the pathways and transcription factors implicated by the transcriptional data are common to both mutants.
Similar(5)
This web-based application enables the exploration of pathway networks relevant to experimental protein expression array data [ 20].
Exploration of signalling pathways in our study showed that PI3/Akt pathway seemed to be more activated than ERK1/2 pathway in GCA patients compared to controls.
Further exploration of these pathways show that they indeed contain the Sos-Ras-Raf-MEK1-ERK1/2 pathaty that regulates a set of critical functions such as cytokine production, cellular growth and differentiation, cell survival, apoptosis and migration.
Gene expression studies allow for the identification of significantly dysregulated genes but can limit the exploration of biological pathways.
To conduct an untargeted, high resolution exploration of metabolic pathways that was altered in association with hepatic steatosis in adolescents.
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