expand dose

USAGE SUMMARY

The phrase "expand dose" is not standard in written English and may cause confusion.
It could be used in a medical or scientific context when referring to increasing the amount of a medication or substance administered. Example: "The doctor decided to expand the dose of the medication to achieve better results in the patient's treatment."

Science

Human-verified examples from authoritative sources

Exact Expressions

1 human-written examples

One patient had febrile neutropenia grade 3, neutropenia grade 4, leukocytopenia grade 3 and thrombocytopenia grade 3 and the other patient had febrile neutropenia grade 4, leukocytopenia grade 4, thrombocytopenia grade 3 and neutropenia grade 4. Because of safety reasons, it was decided not to further expand dose level 6 and this dose level was established as the MTD.

British Journal of Cancer

Human-verified similar examples from authoritative sources

Similar Expressions

59 human-written examples

Screening experiments were carried out in duplicate and expanded dose responses with identified leads were performed at least in triplicate.

BMC Cancer

Moreover, some cumulative myelotoxicity was observed in the 13 patients treated at the expanded dose level (Table 3b).

British Journal of Cancer

If no additional DLT was observed at the expanded dose level (i.e., 1/6 experienced a DLT), the dose was escalated.

British Journal of Cancer

The irinotecan dose was further de-escalated to 110 mg m−2, and three more patients were treated at this expanded dose level.

British Journal of Cancer

At an irinotecan dose level of 130 mg m−2, one of the first three patients developed neutropenic fever during course 1, and one of two additional patients treated at that expanded dose level also developed neutropenic fever during Course 1.

British Journal of Cancer

For expanded dose-response experiments, additional doxorubicin and mitoxantrone were purchased from Sigma while gemcitabine, mithramycin, and thioTEPA were obtained through the NCI/NIH Developmental Therapeutic Program.

BMC Cancer

The phase I trials of gefitinib were unusual in using expanded dosing cohorts so as to provide early opportunity for investigation of end points other than simply the MTD.

British Journal of Cancer

Therefore, the TILs that we have generated have the capacity to expand to doses required for therapeutic protocols.

Plosone

Where specific toxicities were not considered to be drug related, dose escalation was continued without expanding the dose level.

British Journal of Cancer

Drug-resistant IAV was modeled by increasing the in vivo IC50 values for each drug and expanding the dose range to maximum 400 mg, given that higher doses may be needed under these conditions.

CPT: Pharmacometrics and Systems Pharmacology

Expert writing Tips

Best practice

When discussing medical treatments or scientific experiments, consider using more common and precise terms like "increase the dosage" or "escalate the dose" for clarity.

Common error

Using "expand dose" can be vague. Be specific about whether you mean increasing the amount, the duration, or the range of the dose.

Linguistic Context

The phrase "expand dose" primarily functions as a verb phrase followed by a noun. The verb "expand" acts upon the noun "dose", indicating an action of increasing or broadening the amount or range of a substance, typically in a medical or scientific context. As Ludwig AI indicates, the phrase might be considered somewhat unusual in general English.

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, while grammatically acceptable, the phrase "expand dose" is relatively rare and primarily found in scientific and medical contexts. Ludwig AI highlights that it might not be the most common or clearest phrasing. Consider using alternatives like "increase the dosage" or "escalate the dose" for improved clarity. The phrase's function is to describe increasing the amount of a substance, but being more specific will enhance communication, especially given its infrequent usage in general language.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

increase the dosage

Replaces "expand" with a more common synonym "increase", focusing on the amount of medication.

escalate the dose

Uses "escalate" to suggest a gradual increase in dosage, implying a step-by-step approach.

augment the dose

Replaces "expand" with "augment", which means to supplement or make larger.

enlarge the dose

Uses "enlarge" to describe making the dose bigger, focusing on physical size or quantity.

broaden the dose range

Focuses on increasing the range of possible doses rather than a specific instance.

extend the dosage

Uses "extend" suggesting lengthening the duration or scope of the dose's effect.

amplify the dose

Emphasizes the effect of increasing the dose, suggesting a magnified impact.

enhance the dose effect

Focuses on improving or intensifying the outcome of the dose, not just increasing the amount.

maximize the dosage

Suggests increasing the dose to its highest possible or allowable level.

increase the dose interval

Instead of changing the dose itself, it describes expanding the time between doses.

FAQs

What does "expand dose" mean in a medical context?

In a medical context, "expand dose" refers to increasing the quantity or dosage of a medication or treatment. However, it's more common to use phrases like "increase the dosage" or "escalate the dose".

What are some alternatives to the phrase "expand dose"?

Alternatives to "expand dose" include "increase the dosage", "escalate the dose", or "augment the dose". The best choice depends on the specific context.

Is "expand dose" a commonly used phrase in scientific literature?

While "expand dose" appears in some scientific literature, it is not as common as other terms like "increase the dose" or "dose escalation". Using more standard terminology can improve clarity and readability.

How can I use "expand dose" correctly in a sentence?

You can use "expand dose" to describe the action of increasing a dose. For example, "The doctor decided to expand the dose of the medication." However, consider replacing it with more conventional terms for better clarity such as "increase the dosage".