establishing an indication

USAGE SUMMARY

The phrase "establishing an indication" is correct and usable in written English.
It can be used in contexts where you are referring to the process of creating or defining a sign, signal, or suggestion about something. Example: "The research aims at establishing an indication of the effectiveness of the new treatment."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

2 human-written examples

Assessment of the degree of tumour vasculature of liver metastases would be a way of establishing an indication for the utility of TNF- α in this setting.

British Journal of Cancer

Until then it seems that Levomepromazine needs to be considered for use in accordance to expert clinical knowledge and by establishing an indication for its use on ethical considerations, weighing the benefit and harm for an individual patient in clinical practice.

BMC Palliative Care

Human-verified similar examples from authoritative sources

Similar Expressions

58 human-written examples

Micro- and macroscopic examination of the LCD was performed to establish an indication of the cause of color change.

Displays

Our study aims were (1) to demonstrate the effects of pre-analytical steps, collection and pre-processing techniques on salivary protein detection and (2) to establish an indication of salivary reference intervals for 3 biomolecules of clinical interest.

Clinical and Translational Medicine

Although the clinical role and significance of the Dos regulon in human TB is yet to be established, an indication of its clinical relevance emerges by its ~50-fold overexpression in Mtb Beijing (W2) clinical strains (Ref. 153) and the strong immune responsiveness of latently infected patients to the DosR regulon antigens (Refs 154, 155).

Expert Reviews in Molecular Medicine

A high-resolution or multislice thoracic CT scan must be available at a maximum of 24 h after clinical indication has been established (A-II).

Annals of Oncology

These findings strongly suggest a potential value in employing such composite endpoints in future prospective small studies designed to establish an early indication of efficacy.

Arthritis Research and Therapy

GPRD data do not have directly linked information detailing the reasons for being referred for surgery, so we were unable to establish an exact indication.

BMJ Open

However, it would not be appropriate to establish a new indication without randomized controlled trial data to confirm these findings, similar to those recently conducted to study the antidiabetic properties of colesevelam (22).

Diabetes Care

In turn, Mr. Steinberg, the spokesman for the World Jewish Congress, said the latest Swiss actions seemed an indication that moves toward establishing a Holocaust fund were under way.

The New York Times

The objective of this study was to establish an initial set of indications and contraindications for the use of engineered tissues for replacement of TMJ anatomic components.

Journal of Oral and Maxillofacial Surgery

Expert writing Tips

Best practice

In medical contexts, specify whether "establishing an indication" refers to a diagnostic marker, treatment protocol, or other relevant measure.

Common error

Avoid using "establishing an indication" in contexts where a more specific verb like "identifying", "determining", or "defining" would provide greater clarity. For instance, instead of "establishing an indication of interest", consider "identifying a sign of interest".

Linguistic Context

The phrase "establishing an indication" functions as a gerund phrase acting as a noun. It typically describes the action of setting up a sign or signal that something is the case. Ludwig's analysis of real-world examples confirms this usage.

Expression frequency: Uncommon

Frequent in

Science

66%

News & Media

16%

Encyclopedias

3%

Less common in

Wiki

3%

Formal & Business

0%

Reference

0%

Ludwig's WRAP-UP

In summary, "establishing an indication" is a gerund phrase functioning as a noun, commonly used in formal and scientific contexts to describe the process of setting up a sign or signal for something. Ludwig AI highlights its prevalence in academic and scientific publications, emphasizing its role in justifying or demonstrating specific courses of action, particularly in medical and scientific domains. While grammatically correct, it's essential to ensure precise usage, avoiding overly broad applications and opting for more specific verbs when clarity is paramount. As shown in the analyzed examples, this phrase is useful for describing the process of defining or creating a rationale for a treatment, diagnosis, or other action. The most authoritative source, as extracted by Ludwig, include journals such as British Journal of Cancer and BMC Palliative Care.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

determining a need

Focuses on the process of figuring out the necessity of something, slightly different from setting up a signal.

ascertaining a requirement

Highlights the process of finding out what is needed, somewhat different in emphasis.

identifying a necessity

Highlights the act of pinpointing something that is required or essential.

defining a rationale

Emphasizes creating a logical basis or justification, rather than just a sign or signal.

setting criteria

Refers to creating a set of standards or benchmarks, differing from just indicating something.

developing guidelines

Involves creating a set of recommendations, more structured than simply establishing an indication.

creating a diagnostic criterion

Specifically relates to establishing a standard for diagnosis, limiting the scope.

formulating a standard

Focuses on creating a norm or benchmark, more formal and structured.

laying down a principle

Refers to setting a fundamental rule or belief, which is a broader concept.

devising a method

Emphasizes the creation of a systematic approach, deviating from the indication aspect.

FAQs

How can I use "establishing an indication" in a sentence?

You can use "establishing an indication" to describe the process of determining that something is a sign or symptom of a particular condition or situation. For example, "Assessment of the degree of tumour vasculature of liver metastases would be a way of "establishing an indication" for the utility of TNF- α in this setting."

What does it mean to "establish an indication" in medicine?

In a medical context, "establishing an indication" typically refers to identifying the specific conditions or symptoms that warrant a particular treatment, test, or procedure. It involves demonstrating that the potential benefits outweigh the risks.

What's a good alternative to "establishing an indication"?

Depending on the context, you might use alternatives like "determining a need", "defining a rationale", or "identifying a necessity" to convey a similar meaning with slightly different emphasis.

What factors are considered when "establishing an indication" for a new drug?

Factors considered often include clinical trial data, safety profiles, efficacy, and a comparison with existing treatments. Regulatory bodies like the FDA play a crucial role in reviewing these factors to determine if the drug's benefits justify its risks for the proposed indication.