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According to the underlying cellular pathophysiology, these diverse disorders have been subsumed under the term "ciliopathies".
They have enormous therapeutic potential, and have emerged as genetic targets for diverse disorders ranging from inherited cardiac arrhythmias to myopathies.
The continued development of animal models is vital for the understanding and treatment of the many diverse disorders that occur in women.
Not surprisingly, deregulation of REST and ncRNAs are both implicated in the molecular pathophysiology underlying diverse disorders that range from brain cancer and stroke to neurodevelopmental and neurodegenerative diseases.
Damage to this system causes diverse disorders of posture and of balance control [2] [7].
Aberrant REST expression and function are implicated in diverse disorders including cancer [8], neurodegeneration [9] and neurodevelopmental diseases [10].
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Here, we describe this unique resource for the study of sickle cell disease, including novel haplotype-specific polymorphisms that affect disease severity, as well as for the development of patient-specific therapeutics for this phenotypically diverse disorder.
XLMR is a genetically diverse disorder arising from mutation or duplication of genes across the X chromosome, including MECP2.
The studies outlined above concluded that mental illness is a complex and diverse disorder, and that there is need to employ a multi-dimensional approach for the diagnosis and management of mental illness in public health institutions.
The relationship between alcohol use, violence, and diverse psychiatric disorders, including Posttraumatic Stress Disorder (PTSD), has been shown in population-wide studies [ 3].
Furthermore, attention problems are a non-specific symptom and are prevalent in children and adolescents with diverse psychiatric disorders [ 31], e.g. depressive disorder.
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