developmental cell death

USAGE SUMMARY

"developmental cell death" is correct and usable in written English. You can use it in contexts discussing biological processes, particularly in developmental biology or apoptosis. For example, "During embryonic development, developmental cell death is crucial for shaping the final structure of the organism." Alternative expressions include "programmed cell death" and "apoptotic cell death."

✓ Grammatically correct

Science

Academia

Human-verified examples from authoritative sources

Exact Expressions

48 human-written examples

Xu D, Li Y, Arcaro M, Lackey M, Bergmann A. The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila.

Harvard University

Finally, we find Dscam dosage-dependent defects in developmental cell death and amacrine cell spacing, relevant to the increased cell death and other disorders observed in Down syndrome mouse models and human patients, in which Dscam is present in three copies.

Developmental Biology

Mutations in Dscam cause the fasciculation of dendrites of neighboring homotypic neurons, indicating a role in self-avoidance among cells of a given type, a disruption of the non-random patterning of their cell bodies, and a decrease in developmental cell death in affected cell populations.

Developmental Biology

Transcription factors, guidance molecules, extracellular matrix proteins, neurotrophic factors, and cell death-regulating factors of the Bcl-2 family and caspases, have all been reported to be involved in the processes of formation of a precise retino-collicular map, and regulation of developmental cell death.

Progress in Retinal and Eye Research

Here we characterize the developmental cell death of mouse cortical interneurons in vivo, in vitro and after transplantation.

Duke University

We studied the retinas of transgenic mice (Ser 6) expressing the Pro347Ser mutant rhodopsin gene during developmental cell death (age 7 days) and photoreceptor degeneration (age 21 days).

Duke University

Human-verified similar examples from authoritative sources

Similar Expressions

12 human-written examples

Alternatively, it is possible that the developmental cell deaths that shape the tissues in Bax −/− Bak −/− mice are mediated by 'BCL-2-regulated' independent mechanisms, perhaps involving the 'death receptor' apoptotic pathway.

Cell Death and Disease

Our data indicate that mild OPA1 overexpression is compatible with life and blunts damage of highly metabolically active organs in response to apoptotic, necrotic, and atrophic stimuli by reducing cytochrome c release and mitochondrial dysfunction, thereby highlighting the importance of cristae shape in tissue homeostasis and non-developmental cell death.

Cell Metabolism

Many of the effectors of this developmental cell-death programme are highly expressed in the developing brain, making it more susceptible to accidental activation of the death machinery.

Bioscience Reports

Developmental neuronal cell death is critically regulated by the pro-death protein Bax.

Behavioural Brain Research

As cortical development proceeds, NSPC shift from being highly proliferative and self-renewing to being relatively quiescent, reducing their overall number either through a series of non-renewing symmetrical cell divisions, developmental programmed cell death, or perhaps even migration [3], [4], [5].

Plosone

Expert writing Tips

Best practice

Pair this phrase with verbs like "regulate", "induce", "block" or "undergo" to describe experimental or biological dynamics.

Common error

Avoid using "developmental cell death" to describe necrosis or death caused by external trauma (like toxins or physical injury). These are distinct processes; the former is a programmed, functional event while the latter is typically chaotic and pathological.

Linguistic Context

This phrase serves as a technical noun phrase composed of an attributive adjective ("developmental") modifying a compound noun ("cell death"). According to Ludwig AI, it functions as a specific subject or object in scientific discourse to categorize a precise biological phenomenon.

Expression frequency: Common

Frequent in

Science

75%

Academia

20%

News & Media

5%

Less common in

Formal & Business

2%

Encyclopedias

2%

Wiki

1%

Ludwig's WRAP-UP

The phrase "developmental cell death" is a robust and essential term in the biological sciences. Ludwig's data reveals it is used by high-authority institutions like Harvard University and in leading journals such as ScienceDirect and PlosOne. It refers to the genetically programmed elimination of cells that is vital for shaping tissues and organs during development. Unlike pathological death, this process is seen as a constructive part of an organism's lifecycle. Writers should ensure they use it specifically in developmental contexts to maintain technical accuracy and avoid confusion with other types of cellular demise.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

programmed cell death

Broadens the scope to any genetically determined cell elimination process

apoptotic cell death

Specifies the biochemical mechanism (apoptosis) often involved

naturally occurring cell death

Emphasizes that the process is a normal part of life cycles

physiological cell death

Distinguishes the process from pathological or accidental death

morphogenetic cell death

Focuses on the role of death in shaping tissue and organ structure

cellular suicide

Uses more metaphorical language to describe the active nature of the process

terminal cell differentiation

Frames the death as the final stage of a cell's specialized life

active cell death

Highlights that the process requires energy and genetic activation

selective cell elimination

Describes the functional outcome of removing specific cells

programmed senescence

Often used when referring to the aging or deterioration phase of cells

FAQs

What is the difference between "developmental cell death" and "programmed cell death"?

While often used interchangeably, "programmed cell death" is a broader term for any cell death following a genetic program. "developmental cell death" specifically locates this process within the growth and maturation phase of an organism.

Can I use "apoptotic cell death" instead?

Yes, if you are referring to the specific morphological pathway. You can say "apoptotic cell death" to emphasize the mechanism rather than the developmental timing.

Is "developmental cell death" the same as necrosis?

No. Unlike "necrosis", which is typically accidental and inflammatory, "developmental cell death" is a highly regulated and clean process necessary for healthy growth.

What can I say instead of "developmental cell death" in a general context?

Depending on the focus, you might use "naturally occurring cell death" or "morphogenetic cell death".