Sentence examples for determinant in the pathogenesis of from inspiring English sources

Furthermore, the ability of S. aureus to form biofilms and colonize medical devices is regarded as an important virulence determinant in the pathogenesis of this bacterium.

Angiotensin converting enzyme (ACE) is a critical determinant in the pathogenesis of various cardiovascular diseases and in the control of male fertility.

Acquisition of Fe and Fe-complexes has long been recognized as a major determinant in the pathogenesis of Neisseria spp., and some of their high-affinity iron uptake systems are important virulence factors in bacteria.

Nowadays, estrogen deficiency (severe or mild) should be considered one of the key steps in the promotion of bone loss in men (Riggs et al 1998) as well as a major determinant in the pathogenesis of age-related male osteoporosis (Carani et al 1997; Rochira et al 2000; Rochira et al 2006).

As such, microvascular alterations have been advocated as one of the main determinants in the pathogenesis of sepsis-related organ dysfunction through multiple mechanisms, including endothelial dysfunction, impaired inter-cellular communication, altered glycocalyx, adhesion and rolling of white blood cells and platelets, and altered red blood cell deformability [60].

Interleukin-4 and IL-13 have been shown to modulate lung inflammation in animal models and thus the presence or absence of these cytokines in the lung may be important determinants in the pathogenesis of BPD [ 16, 28].

As such, microvascular alterations have been advocated as one of the main determinants in the pathogenesis of sepsis-related organ dysfunction through multiple mechanisms, including endothelial dysfunction, impaired inter-cellular communication, altered glycocalyx, adhesion and rolling of white blood cells and platelets, and altered red blood cell deformability [ 60].

Alterations of the myogenic process were proposed to play a determinant role in the pathogenesis of muscle atrophy [5].