Sentence examples for pivotal in the pathogenesis of from inspiring English sources

It is now thought that Aβ is pivotal in the pathogenesis of Alzheimer's disease, and that reducing brain Aβ levels may help to treat or prevent the disease.

Endothelial cell activation and apoptosis are thought to be pivotal in the pathogenesis of SSc.

Angiogenic and angiostatic factors have been found to be pivotal in the pathogenesis of CNV.

Inflammatory cytokines are pivotal in the pathogenesis of rheumatoid arthritis (RA) [ 1].

While the posterior sclera seems pivotal in the pathogenesis of glaucoma [ 33], the significance of the anterior sclera in this disease is not yet clear.

Endothelial cell activation and apoptosis are thought to be pivotal in the pathogenesis of this disease, but the mechanisms that mediate this remain unknown.

Inflammation plays a pivotal role in the pathogenesis of atherosclerosis.

For example, HIF-2α, the product of the EPAS1 gene, plays a pivotal role in the pathogenesis of RA34.

Wnt/β-catenin signaling has a pivotal role in the pathogenesis of hepatocellular carcinoma (HCC).

Inflammation may play a pivotal role in the pathogenesis of pulmonary arterial hypertension (PAH).

Platelet activation plays a pivotal role in the pathogenesis of acute coronary syndromes.