There are many reasons for decreased FIB concentration, including easily detectable variables such as blood loss, dilution, hypothermia and acidosis, and harder to detect variables such as consumption, hyperfibrinolysis and measurement-specific variability.
With aging, cellular and molecular damage accumulates, ultimately giving rise to deficits that are visible by laboratory measures and as macroscopically detectable variables.
In summary, the HIV-specific CD8+ T-cell responses of B*27/57 neg LTNP/EC were readily detectable, variable in magnitude and narrow in breadth (Migueles et al., 2000, Migueles et al., 2002).
A wide spectrum of hormonally active exposure biomarkers were detectable and variable among young girls, with high maximal concentrations (> 1,000 μg/L) found for several analytes.
The team established that urinary metabolites of phenols, phthalates, and phytoestrogens in children are detectable and variable enough to make meaningful comparisons.
With the exception of Myc, each of these proteins was detectable at variable levels across non-diseased vascular tissues, ranging from 50%% of normal tissues displaying Nanog and Klf4 immunoreactivity to 90%% of normal tissues displaying Oct4 immunoreactivity (Table 2).
LCL patients represent an intermediate group between ML and VL, displaying a detectable, but variable humoral and cellular immune response with production of both Th1 and Th2 cytokines, undergoing a shift towards the Th1/cellular pole after successful treatment [ 4].
With the exception of Myc (which was only present in a subset of benign, borderline, and malignant tumors), Oct4, Nanog, Sox2, and Klf4 were detectable at variable levels across both normal and diseased tissues.
We also showed that in addition to epithelial cells, stromal GLUT4 immunoreactivity was detectable and variable in cultured human endometrial tissues treated with hCG, E2, and P4 (Fig. 4).
The pilot study sampled a relatively small population to determine whether urinary biomarkers of the chemicals of concern would be detectable and variable enough for meaningful comparisons of their concentrations in relation to outcomes of female growth and development.
We initially injected subretinally 1 month-old C57/BL6 mice with improved dual AAV vectors (dose of each vector/eye: 2 × 10 GC) and found that 12 out of 24 (50%) injected eyes had detectable albeit variable levels of full-length ABCA4 protein by Western blot [Figure 5A; ABCA4 protein levels in the ABCA4-positive eyes: 2.8 ± 0.7 a.u. (mean ± standard error of the mean)].
