demonstrate proof of principle

USAGE SUMMARY

"demonstrate proof of principle" is correct and usable in written English.
You can use it when you are trying to show or prove that a concept or idea works in theory. For example, "He set out to demonstrate proof of principle that the new vaccine was effective."

✓ Grammatically correct

Science

Academia

News & Media

Human-verified examples from authoritative sources

Exact Expressions

23 human-written examples

When making predictions, I have two criteria: the laws of physics must be obeyed and prototypes must exist that demonstrate "proof of principle".

The New York Times

Oblimersen is the first oligonucleotide to demonstrate proof of principle of an antisense effect in human tumors by the documented downregulation of the target Bcl-2 protein.

Seminars in Oncology

It was very difficult to winnow the 26 proposals that were submitted this year down to the five projects we selected". The research projects are intended to demonstrate proof of principle, provide insights and tools for addressing needs or establishing new and innovative ideas and approaches to specific sustainability problems.

Cornell University

The current study used the extreme comparison of ALL with AML clinical samples to demonstrate proof of principle of the approach.

Plosone

Here we utilized chlorpromazine to specifically inhibit clathrin-mediated endocytosis as a model to demonstrate proof of principle.

Bioconjugate Chemistry

We also demonstrate proof of principle that this genome wide functional analysis will enable discovery of novel infection related biology.

Fungal Genetics and Biology

Human-verified similar examples from authoritative sources

Similar Expressions

37 human-written examples

In this study, our objective was to demonstrate proof-of-principle for RNAi therapy of a dominant myopathy in vivo.

Molecular Therapy

To demonstrate proof-of-principle measurement for physiologic change within an active myofascial trigger point (MTrP) undergoing trigger point release (ischemic compression).

Archives of Physical Medicine and Rehabilitation

We demonstrate proof-of-principle by using the gene-based test to replicate several genes known to be associated on the basis of results from a family-based GWAS for height in 11,536 individuals and a DNA-pooling-based GWAS for melanoma in ∼1300 cases and controls.

The American Journal of Human Genetics

Our research spans from discovery of novel molecular markers that underlie differences in drug response to testing novel interventions that tailor drug therapy in patients to demonstrate proof-of-principle.

Duke University

Our results demonstrate proof-of-principle that there is differential expression of volatiles in melanoma.

Plosone

Expert writing Tips

Best practice

When using "demonstrate proof of principle", ensure that you have concrete evidence or preliminary results to support your claim. Avoid using it speculatively.

Common error

Avoid using "demonstrate proof of principle" if your evidence is weak or based on theoretical assumptions only. Use softer terms like "explore the possibility" or "investigate the potential" instead.

Linguistic Context

The phrase "demonstrate proof of principle" functions as a verb phrase, often used to indicate the act of providing initial evidence or validation for a concept. Ludwig AI highlights its use in various scientific and academic contexts.

Expression frequency: Common

Frequent in

Science

70%

Academia

20%

News & Media

10%

Less common in

Formal & Business

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

The phrase "demonstrate proof of principle" is a commonly used expression, particularly in scientific and academic fields, to indicate that initial evidence supports a concept's viability. As Ludwig AI confirms, the phrase is grammatically correct and widely accepted. While "demonstrate proof of principle" is most frequently found in scientific literature, it also appears in academic and news contexts. When using this phrase, it is important to have concrete evidence to support the claim and avoid overstating preliminary findings. Alternative phrases, such as "establish feasibility" or "validate the concept", can be used to express similar ideas.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

establish feasibility

Focuses on showing that something is possible and practical.

demonstrate the validity

Focuses on showing that something is accurate and well-founded.

validate the concept

Emphasizes confirming the soundness of an idea.

confirm the viability

Highlights proving that something can work successfully.

substantiate the rationale

Focuses on backing up the reasoning behind something.

verify the hypothesis

Specifically related to scientific contexts, confirming a proposed explanation.

prove the effectiveness

Highlights demonstrating that something achieves the desired result.

show it works in practice

Emphasizes real-world application and successful execution.

illustrate the mechanism

Highlights demonstrating the underlying process.

provide evidence for concept

Emphasis on presenting supporting data for an idea.

FAQs

How can I use "demonstrate proof of principle" in a sentence?

You can use "demonstrate proof of principle" to indicate that you are showing initial evidence that a concept or idea is viable. For example, "The study aims to "demonstrate proof of principle" for a new cancer treatment".

What does "demonstrate proof of principle" mean?

It means to show that a concept or idea is feasible and can work in practice, often through initial experiments or prototypes. It's about showing the idea has potential, not necessarily that it's fully developed.

What can I say instead of "demonstrate proof of principle"?

You can use alternatives like "establish feasibility", "validate the concept", or "confirm the viability", depending on the context.

Is it appropriate to use "demonstrate proof of principle" in a business context?

Yes, "demonstrate proof of principle" is appropriate in a business context when you want to show that a new product, service, or strategy has potential. It's often used when presenting initial findings or pilot projects.